GENETICS

2. Coexistence of more than one mitochondrial DNA genotype within the same cell or individual.
3. Genome editing technology adapted from a bacterial adaptive immune defense against bacteriophages.
4. Scientist whose X-ray diffraction image of DNA was instrumental in elucidating its double-helical structure.
6. Neurogenetic syndrome resulting from loss of maternally expressed UBE3A on chromosome 15.
8. Phenomenon in which a single gene influences multiple seemingly unrelated phenotypic traits.
11. Ribonucleoprotein enzyme responsible for maintaining the length of chromosome ends.
12. Genetic phenomenon in which successive generations develop a disorder at an earlier age or with increasing severity.

1. Epigenetic mechanism in which gene expression depends on the parent of origin.
5. Scientist who proposed the two-hit hypothesis for the development of hereditary cancers.
7. Presence of two or more genetically distinct cell populations arising from a single zygote.
9. French geneticist who identified trisomy 21 as the chromosomal basis of Down syndrome.
10. Random inactivation of one X chromosome in female somatic cells.