GENETICS

3. Neurogenetic syndrome resulting from loss of maternally expressed UBE3A on chromosome 15.
7. Random inactivation of one X chromosome in female somatic cells.
8. French geneticist who identified trisomy 21 as the chromosomal basis of Down syndrome.
9. Genome editing technology adapted from a bacterial adaptive immune defense against bacteriophages.
10. Scientist whose X-ray diffraction image of DNA was instrumental in elucidating its double-helical structure.
11. Presence of two or more genetically distinct cell populations arising from a single zygote.
12. Epigenetic mechanism in which gene expression depends on the parent of origin.

1. Ribonucleoprotein enzyme responsible for maintaining the length of chromosome ends.
2. Phenomenon in which a single gene influences multiple seemingly unrelated phenotypic traits.
4. Scientist who proposed the two-hit hypothesis for the development of hereditary cancers.
5. Genetic phenomenon in which successive generations develop a disorder at an earlier age or with increasing severity.
6. Coexistence of more than one mitochondrial DNA genotype within the same cell or individual.