Get to Know Immunology Basics

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Across
  1. 4. an immune response that does not involve antibodies but rather involves antigen presenting cells and T-cell lymphocytes
  2. 6. a molecule that stimulates an immune response by activating leukocytes that fight disease
  3. 10. genes
  4. 13. transcription factor that helps activate the expression of many
  5. 14. cell, a lymphocyte subtype that develops and matures in the bone marrow
  6. 15. a cell wall component of gram negative bacteria
  7. 16. these are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigen
  8. 20. lymphocyte that matures in the thymus
  9. 21. part of an innate immune response that kills infected cells kills by apoptosis
  10. 24. a cytokine that is critical for immunity against viral infections and is commonly known as type II interferon
  11. 25. subpopulation of T cells that suppress immune responses
  12. 27. an immune cell that links the innate and adaptive arms of the immune system
  13. 29. leukocytes with multi-lobed nuclei and cytoplasmic granules
  14. 30. a medication regimen used to manage and treat human immunodeficiency virus
Down
  1. 1. the end stage of disease in a HIV infection
  2. 2. group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances
  3. 3. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  4. 5. cell surface ligands for leukocyte integrins
  5. 7. transcription factor expressed in Treg cells that is needed for their function
  6. 8. a virus that attacks the body's immune system and if not treated can lead to AIDS
  7. 9. a blood test marker for inflammation in the body
  8. 11. Y-shaped protein used by the immune system to identify and neutralize foreign objects
  9. 12. highly pro-inflammatory cytokine produced by macrophages and T cells
  10. 16. reaction which occurs within an organism for the purpose of defending against foreign invaders
  11. 17. involved in stimulating B cells to produce antibody against extracellular pathogens
  12. 18. crystallized fragment of an antibody
  13. 19. general designation of many of the different cytokines
  14. 22. an immunoglobulin expressed on B cell surfaces
  15. 23. receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
  16. 26. short DNA sequences that serve as the binding sites and allow for somatic recombination
  17. 28. a subtype of a thymus-derived lymphocyte that expresses the co-receptor protein CD4