Get to Know Immunology Basics

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Across
  1. 1. a blood test marker for inflammation in the body
  2. 3. group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances
  3. 6. these are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigen
  4. 9. lymphocyte that matures in the thymus
  5. 11. transcription factor expressed in Treg cells that is needed for their function
  6. 13. cell surface ligands for leukocyte integrins
  7. 15. crystallized fragment of an antibody
  8. 16. reaction which occurs within an organism for the purpose of defending against foreign invaders
  9. 17. highly pro-inflammatory cytokine produced by macrophages and T cells
  10. 19. a molecule that stimulates an immune response by activating leukocytes that fight disease
  11. 20. a lymphocyte subtype that develops and matures in the bone marrow
  12. 23. the end stage of disease in a HIV infection
  13. 27. genes
Down
  1. 2. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  2. 4. a subtype of a thymus-derived lymphocyte that expresses the co-receptor protein CD4
  3. 5. part of an innate immune response that kills infected cells kills by apoptosis
  4. 6. general designation of many of the different cytokines
  5. 7. subpopulation of T cells that suppress immune responses
  6. 8. a cytokine that is critical for immunity against viral infections and is commonly known as type II interferon
  7. 10. a virus that attacks the body's immune system and if not treated can lead to AIDS
  8. 12. leukocytes with multi-lobed nuclei and cytoplasmic granules
  9. 14. an immunoglobulin expressed on B cell surfaces
  10. 17. involved in stimulating B cells to produce antibody against extracellular pathogens
  11. 18. Y-shaped protein used by the immune system to identify and neutralize foreign objects
  12. 21. an immune response that does not involve antibodies but rather involves antigen presenting cells and T-cell lymphocytes
  13. 22. a cell wall component of gram negative bacteria
  14. 24. an immune cell that links the innate and adaptive arms of the immune system
  15. 25. a medication regimen used to manage and treat human immunodeficiency virus
  16. 26. receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
  17. 28. short DNA sequences that serve as the binding sites and allow for somatic recombination
  18. 29. transcription factor that helps activate the expression of many