Get to Know Immunology Basics

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Across
  1. 4. an immune response that does not involve antibodies but rather involves antigen presenting cells and T-cell lymphocytes
  2. 6. crystallized fragment of an antibody
  3. 8. involved in stimulating B cells to produce antibody against extracellular pathogens
  4. 9. Y-shaped protein used by the immune system to identify and neutralize foreign objects
  5. 10. leukocytes with multi-lobed nuclei and cytoplasmic granules
  6. 12. the end stage of disease in a HIV infection
  7. 13. a lymphocyte subtype that develops and matures in the bone marrow
  8. 16. highly pro-inflammatory cytokine produced by macrophages and T cells
  9. 18. a subtype of a thymus-derived lymphocyte that expresses the co-receptor protein CD4
  10. 20. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  11. 23. an immunoglobulin expressed on B cell surfaces
  12. 25. short DNA sequences that serve as the binding sites and allow for somatic recombination
  13. 26. reaction which occurs within an organism for the purpose of defending against foreign invaders
Down
  1. 1. group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances
  2. 2. transcription factor that helps activate the expression of many pro-inflammatory genes
  3. 3. transcription factor expressed in Treg cells that is needed for their function
  4. 5. a cytokine that is critical for immunity against viral infections and is commonly known as type II interferon
  5. 7. an immune cell that links the innate and adaptive arms of the immune system
  6. 8. lymphocyte that matures in the thymus
  7. 11. part of an innate immune response that kills infected cells kills by apoptosis
  8. 14. a medication regimen used to manage and treat human immunodeficiency virus
  9. 15. cell surface ligands for leukocyte integrins
  10. 16. subpopulation of T cells that suppress immune responses
  11. 17. a virus that attacks the body's immune system and if not treated can lead to AIDS
  12. 18. a blood test marker for inflammation in the body
  13. 19. a cell wall component of gram negative bacteria
  14. 21. a molecule that stimulates an immune response by activating leukocytes that fight disease
  15. 22. receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
  16. 24. these are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigen
  17. 26. general designation of many of the different cytokines