Hackenbees Day to Day 2026

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Across
  1. 4. small model protein that possesses no tryptophan residues
  2. 6. around 15 kda, camelids or synthetic
  3. 8. 14-amino-acid peptide sequence from the cellular protein tubulin, site specific modification
  4. 11. sometimes as a group we have this three times a month
  5. 16. click type reaction between a strained cyclooctane and azido group
  6. 17. ________ formation; our latest cpp mechanistic investigation
  7. 18. standard bacteria medium
  8. 20. group coffee cost in cents
  9. 21. special chip and matrix
  10. 22. needed to amplify dna
  11. 23. binds reversibly to sugars, trivalent boron containing
  12. 25. a long week of spending time with each other and numbers
  13. 27. protects amine groups in organic and peptide synthesis
  14. 29. cftr nanobody in latest publication was modified with this CPP
  15. 32. used to monitor or find your compound
  16. 33. compounds used as antidote for nerve agents (poisoning)
  17. 34. deazaflavin as a catalyst
  18. 37. first names: Gottfried Wilhelm
  19. 39. removed with 2% tfa
  20. 41. codon replaced to introduce non-canonical amino acids
  21. 43. N-terminal protein modification, requires glycine and lpetgg
  22. 44. you are probably this
  23. 46. not tap or ultra pure
  24. 48. you use it almost everyday if you're a chemist, invented in 1950
  25. 49. catalyst that can be found in space
  26. 50. uncommon PTM that controls bacterial signaling and gene expression
  27. 51. this chemical mixes easily with both water-based and oil-based substances, used to clean glassware
  28. 53. core of common reagent that produces yellow color when reacting with free thiols
Down
  1. 1. chemical reaction and motorvehicle brand
  2. 2. hplc that runs on windows XP
  3. 3. made from three amino acids, uses ATP, body's "master antioxidant", used in stability tests
  4. 5. not cysteine, "21st amino acid"
  5. 7. must do this for amine coupling
  6. 9. RNA pol copying DNA to mRNA
  7. 10. routine model fluorescent protein used in delivery experiments
  8. 12. seen in internucleotide linkages, a non-bridging oxygen is replaced by a sulfur atom
  9. 13. barrier in mucus on surface of endothelial cells
  10. 14. jellyfish origin
  11. 15. used in synthesis of semi-synthetic full length tau
  12. 19. serum in dmem
  13. 24. frequently used cationic hydrophobic additive
  14. 26. very mild azide reduction; trivalent phosphine and water
  15. 28. you must do this to your peptide on resin
  16. 30. contains 8 free thiols after reduction, very large
  17. 31. protein purifier
  18. 35. multivalent cpp conjugation to lysine residues
  19. 36. how to sterilize liquid and dry goods
  20. 38. found only in dna, not rna
  21. 40. for checking fractions of a non UV active compound
  22. 42. usually when we have a bbq
  23. 44. peptide purifier
  24. 45. s1 bacterial organism used by us
  25. 47. another way to measure non UV active compound
  26. 52. tubulis adc in clinical trials