Haematopoiesis and innate immunity

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Across
  1. 2. Where T cells are made
  2. 5. There are several hundred of these small immune organs in the human body (5,5)
  3. 8. Found in gram negative bacteria, binds TLR4. AKA endotoxin.
  4. 13. Another name for a white blood cell
  5. 14. Present in tissues. Highly phagocytic. Differentiates from monocytes.
  6. 15. Abbreviation for a erythroid growth factor used to treat anaemia
  7. 17. (4-4,8) Highly conserved receptor that recognises molecular patterns from bacteria and viruses
  8. 21. Another name for a red blood cell
  9. 22. Growth factor AKA granulocyte macrophage colony stimulating factor
  10. 23. Innate immune cell associated with allergy. Polymorphic nucleus. Granules stain purple.
  11. 25. Innate immune cell with a polymorphic nucleus. Worm and parasite fighter. Granules stain pinkish in a blood smear.
  12. 26. Site of haematopoiesis in the fetus
  13. 27. A higher degree some of you might go on to achieve
  14. 28. Innate immune cell with a polymorphic nucleus. Highly phagocytic.
Down
  1. 1. (7,6,4) Innate immune cell with adaptive immune traits. Mononuclear. Important for tumour immunosurveillance
  2. 3. Abbreviation for a platelet growth factor used to treat thrombocytopenia
  3. 4. The colour of an erythrocyte under the microscope
  4. 6. (4,6) Site of haematopoiesis in adults
  5. 7. (14,4,4) Generates all cells of the blood. Self-renewing and multipotent.
  6. 9. The process by which an innate immune cell "eats" antigens or foreign matter
  7. 10. Our largest organ has an important immunological barrier function
  8. 11. A molecular messenger, can be pro- or anti-inflammatory
  9. 12. Red blood cells uniquely lack this organelle compared to every other cell type in the body
  10. 14. Biggest cell in bloodstream. Mononuclear. Migrates into tissues for differentiation.
  11. 16. Site of red blood cell destruction, and place where adaptive immune responses begin for blood-borne infections
  12. 18. So named because these cytokines interfere with viral replication
  13. 19. Abbreviation for an antigen presenting cell
  14. 20. Mediates adaptive immunity. Mononuclear cell. Can be of the T or B varieties.
  15. 23. A very important fluid containing erythrocytes, leukocytes, antibodies, and clotting factors
  16. 24. Very commonly used animals for immunology research