Hematology - Disorders of White Blood Cells

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Across
  1. 2. The cells seen in Hodgkin’s lymphomas are known as _________ cells
  2. 4. A type of white blood cell that ingests bacteria and foreign particles
  3. 7. Associated with t(14:18), _____ lymphoma
  4. 8. Classic formation seen histologically in multiple myeloma
  5. 9. Most common M protein produced by myeloma cells in multiple myeloma (60%)
  6. 11. Consumption of this can result in pain in lymph nodes
  7. 12. APTT is normal and PT is increase, there would be an issue in the _____ pathway
  8. 13. Where do T Cells mature
  9. 14. Acute lymphoblastic leukemia is the most common ______ cancer
  10. 17. Where do B cells mature
  11. 20. The most common type of white blood cell
  12. 22. Histological feature seen in acute myeloid leukemia
  13. 24. The process by which the body produces new blood cells
  14. 30. A type of normal white blood cell that may increase with bone marrow damage, parasitic infections, or allergic reactions
  15. 31. A type of white blood cell that mediates allergic reactions and defends the body from infection by parasites and bacteria
  16. 32. Secondary organ throughout the body that play a role in the immune system by filtering out foreign particles, such as viruses and bacteria
  17. 33. Transformation of chronic lymphocytic leukemia to a higher-grade lymphoma = _______ transformation
  18. 35. Most predominant cell type in acute lymphoblastic anemia
  19. 36. Multiple punched-out lesions on an skull x-ray is indicative of which condition?
Down
  1. 1. Fusion of a-RARA on chr 17 and PML gene on chr 15, acute ____ leukemia
  2. 3. Seen in chronic lymphocytic leukemia as a result of suppression of normal B cell function
  3. 5. A low number of granulocytes (white blood cells that fight infection)
  4. 6. This lymphoma is described histologically as a “starry sky”
  5. 10. Classification system sometimes used for clinical staging of Hodgkin’s and non-Hodgkin’s lymphomas
  6. 15. APTT is increased and PT is normal, there would be an issue in the _____ pathway
  7. 16. The chromosome associated with chronic myeloid leukemia = _________ chromosome
  8. 18. Nonclassical Hodgkin’s lymphoma = lymphocyte _______
  9. 19. A type of white blood cell that produces antibodies
  10. 21. Age distribution seen in Hodgkin’s lymphoma
  11. 23. Clinical examination finding often associated with leukemias
  12. 25. Cells seen in chronic lymphocytic leukemia on peripheral blood film
  13. 26. _____ is a lysosomal enzyme present in granulocytic and monocytic cells
  14. 27. Histological feature seen in acute myeloid leukemia
  15. 28. The 3 phases of Chronic Myeloid Leukemia are Chronic, Accelerated and ____ Phase
  16. 29. What is the most common cause of leukemia in adults (abbreviation)
  17. 34. Abnormally low fibrinolytic activity resulting in thrombosis