Hematopoiesis 1

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Across
  1. 2. the conglomeration of all body's red blood cells (nucleated, retics, mature) functioning as an organ
  2. 4. the phagocytic cells of the spleen
  3. 9. a disorder present at birth (not necessarily with genetic basis)
  4. 10. the hormone responsible for stimulating the production of red blood cells in the bone marrow
  5. 11. the __________ stem cell is capable of reproduction and differentiation, but not at the same time
  6. 12. phagocytic cells in the liver that are a major site of removal for RBCs affected by immune complexing (Igs, etc.)
  7. 15. the hormone responsible for stimulating the production of platelets in the bone marrow
  8. 16. mitotic hematopoietic cells that have a determined lineage will produce daughter cells of __________ lineage during mitosis
  9. 18. this system consists of bone marrow, liver, lymph nodes, thymus, and spleen
  10. 19. this hematopoetic period occurs at 5-7 weeks of gestation, peaks around 3-5 months, and occurs in the liver
  11. 21. structural part of the spleen containing cords of Billroth and macrophages
  12. 22. the process the spleen does to remove RBC inclusion bodies
  13. 23. spleen component between the lymphatic sheath and red pulp that slowly depletes RBC glucose supply
  14. 24. erythropoietin is produced in this organ
  15. 25. hematopoiesis outside of the bone marrow, usually in the spleen, liver, or kidneys; unusual in adults
  16. 27. a disorder that occurs in family members to a greater degree than chance would allow
  17. 28. this hematopoietic period occurs from 6 months to birth and is when the bone marrow becomes the primary site of hematopoiesis
  18. 31. this hematopoietic period occurs at 19 days of gestation, between weeks six and eight; measurable are Portland, Gower 1, and Gower 2 are all hemoglobins
Down
  1. 1. erythropoietin increases the rate of the __________ shunt
  2. 3. in terms of hematology and hematopoiesis, CSF stands for __________ factors
  3. 5. a disorder transmitted from parent to offspring (hereditary)
  4. 6. the process the spleen does to remove old or abnormal RBCs
  5. 7. erythropoietin regulates the mitosis cycle, retic release, and synthesis of this
  6. 8. a place in the middle of the bone marrow where red cells mature with the help of a nurse cell
  7. 13. the mitotic offspring of stem cells that are committed to either lymphoid or myeloid line differentiation
  8. 14. spleen component containing follicles and germinal centers; site of lymphocyte refinement
  9. 17. this system plays an important role in regulating hematopoiesis via hormones
  10. 20. blood cells produced in the mesoblastic period are primitively __________ in nature
  11. 26. hematopoiesis primarily takes place in the vertebra and sternum for __________
  12. 29. during the mesoblastic period, hematopoietic processes begin in the mesenchymal cells of the __________
  13. 30. thrombopoietin is produced in this organ