Histopathologic and Cytologic Techniques Crossword Puzzle

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Across
  1. 1. Refers to the failure of an organ to reach its normal mature adult size.
  2. 4. Includes entering the details of the specimen in a log book.
  3. 6. This fluid is recommended to be used in fixing liver or spleen.
  4. 9. This is an acid that is most commonly used for routine decalcification.
  5. 11. A fixative that is used to preserve chemical components like enzymes, lipase, phosphatases, mucopolysaccharides, mucin.
  6. 13. A mixture of highly purified paraffin and synthetic plastic polymers.
  7. 14. The purpose of this process is to remove burrs and other irregularities formed during honing.
  8. 17. It is the color of Mycelia during a Pap’s smear staining.
  9. 18. A gangrene that is due to arterial occlusion.
  10. 19. A purified form of nitrocellulose that is soluble in alcohol and ether.
  11. 21. This fluid is the most rapid fixative that is recommended for fixing chromosomes and lymph glands.
  12. 23. A microtome invented by Adams that is the most dangerous due to the exposed knife and is used only to cut celloidin-embedded tissues.
  13. 26. It is a cell death due to a disease.
  14. 27. It is the removal of calcium ions or lime salts from the organic extracellular matrix.
  15. 30. It refers to the drying and wrinkling of the anterior chamber of the eye and cornea.
  16. 32. This solution is recommended for fixation of embryos, pituitary biopsies, and endometrial curettings.
  17. 34. The person who does the grossing and dissecting of tissue specimens received in the laboratory.
  18. 35. It is when a specimen is spread on a slide until it forms an oval smear.
  19. 36. Boat shaped cells seen in Pap’s smear with a tendency to fold or curl on edges.
  20. 39. In the process of dehydration, it can be an Ethanol substitute, while in the process of clearing, it can be used as a Xylene substitute.
  21. 40. It is a chromate fixative thatt is used for chromatin, mitochondria, mitotic figures, golgi bodies, RBC, and colloid-containing tissues.
  22. 41. Cells that are medium-sized and are polyhedral with basophilic and vacuolated cytoplasm seen in Pap’s smear.
  23. 42. It is the routine clearing agent because it is fast-acting but not suited for nervous tissues and lymph nodes.
  24. 43. Refers to the failure of an organ to form an opening.
  25. 44. It is the most commonly used alcohol in fixation.
  26. 46. A clearing agent that is obtained from a citrus fruit.
  27. 48. This is not a routine clearing agent but is recommended for tough tissues.
  28. 50. An alcohol that is the most commonly used dehydrating agent for routine processes because it is non-toxic.
  29. 51. A cardinal sign of inflammation that refers to heat due to transfer of internal heat to the site of injury.
  30. 55. Uses an increasing or ascending concentration of alcohol.
Down
  1. 2. Used for writing when labeling specimens.
  2. 3. This dehydrating agent is toxic when inhaled, ingested, and upon prolonged skin contact.
  3. 5. An atrophy that may develop due to excessive workload.
  4. 7. A clearing agent that has a faint odor and low evaporation rate and is used for clearing eye specimens.
  5. 8. Considered as a mortal sin in histopathology.
  6. 10. It refers to the process of tumor formation.
  7. 12. Done to determine cause of death and the tissue sample is removed from a dead body.
  8. 13. A study of all changes in cells, tissues, organs that underlie a disease.
  9. 15. An alcohol fixative that is used for fixing wet and dry smears, blood smears, and bone marrow tissues.
  10. 16. It is a potent anticoagulant but a weak decalcifying agent.
  11. 20. It is also known as Pre-neoplastic Lesion or Atypical Metaplasia.
  12. 22. A natural vegetable dye from lichens, used mainly in dermatology due to its ability to demonstrate fine and delicate fibers.
  13. 24. When only a part of the mass/organ is removed.
  14. 25. A preservative that is composed of 50% ethanol and 20% carbowax.
  15. 28. This method is done when fixing hard tissues by immersing it in 4% aqueous phenol for 1 to 3 days.
  16. 29. It is when a specimen is applied on slide in a zigzag manner.
  17. 30. A cardinal sign of inflammation that refers to pain due to release of chemicals and substances like bradykinin that stimulates nerve endings for pain.
  18. 31. A stain that demonstrates mucin by adding aluminum hydroxide to carmine.
  19. 32. An alcohol that is recommended for plant and animal microtechniques.
  20. 33. A dehydrating agent that is extremely dangerous and toxic to man.
  21. 37. It is double-purpose because it can fix and dehydrate tissues but evaporates easily and it is highly-flammable.
  22. 38. Presence of this indicates that the decalcification is not yet complete.
  23. 39. It is when affected cells can no longer get back to its normal state.
  24. 45. An increase in tissue or organ size due to an increase in the size of individual cells comprising an organ.
  25. 47. It is under diagnostic cytology that involves examination of cells specifically cells desquamated or shed from epithelial surfaces.
  26. 48. Starting point of disease because it is the basic unit of life.
  27. 49. Cells that are present in Pap’s smear that are smaller than intermediate cells with fried egg appearance.
  28. 52. A type of necrosis seen in acute pancreatitis.
  29. 53. A system developed at national Cancer Institute in December 1988.
  30. 54. This is the most reliable and most accurate method for testing for the completeness of decalcification.