Histopathology Descriptors

2. Cells where the bulbous nucleus bulges into a lumen or space, with the narrow cytoplasm attached to the base
6. Cells arranged in cords, beams, or columns
7. Large, atypical cells with pale or clear cytoplasm migrating individually or in small clusters through the upper layers of an epithelium
11. An architectural pattern that resembles finger-like projections of epithelial cells
13. Sheets of cells are punctured by multiple well-defined, round, rigid extracellular spaces
14. Cells arranged in nests or clusters that mimic the air sacs of the lungs
15. A dense, fibrous, or collagen-rich stromal response triggered by invading tumour cells
16. Bundles of cells intersecting at sharp angles, resembling the skeletal pattern of a fish
18. Completely enclosed by a distinct outer wall of fibrous connective tissue
20. Cells that are round, polygonal, or cuboidal with abundant cytoplasm and distinct cell borders
21. Resembling the small, immature cells found at the base of the outer layer of skin and other tissue linings

1. Cells arranged in circular, hollow structures, often enclosing a central lumen
3. Cells spread widely, uniformly, and randomly throughout a tissue
4. Cells organized into parallel bundles or sheets
5. Cell arrangement that mimics the regular structural organisation of a normal organ
8. Complete loss of standard cellular adhesion
9. Marked variation in the size, shape, and staining of cells and their nuclei
10. Cells that are elongated, wider in the middle, and tapered at the ends
12. Sharply defined, well-demarcated borders
17. A growth pattern where cells actively break through tissue boundaries to invade the surrounding stroma
19. Composed of two distinct cell lineages or tissue types within the same tumour