Homework 1: Crossword Puzzle

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Across
  1. 2. In a severe case of IDA, a symptom of ______ , presenting as concave, cracked nails, can be observed
  2. 4. The two chemical forms of iron are _____ and ferric
  3. 6. The pantry is empty
  4. 10. Most total body iron is present as ___________ iron
  5. 11. In stage 2 and 3 of iron-deficient anemia, this will be increased
  6. 12. Persistent craving and consumption of non-food items that have no nutritional value
  7. 14. Anemia of chronic ___________ 2nd most common cause of anemia
  8. 16. Hereditary hemochromatosis can damage this gland, which regulates several hormone.
  9. 19. Porphyrias are hereditary conditions that impair production of ____ in the heme synthesis pathway
  10. 20. Tissue damage that results from the excessive accumulation of iron
Down
  1. 1. A decrease in all 3 blood cells – red cells, white cells, and platelets: pancytopenia
  2. 3. This stores iron in cells
  3. 5. An increase in red blood cell size, commonly seen in B12 or folate deficiency
  4. 7. Inactivates ferroportin and decreases iron absorption
  5. 8. The vitamin whose deficiency causes megaloblastic anemia, also known as B12
  6. 9. A hallmark sign of sideroblastic anemia in a gram stain shows ___ sideroblasts in bone marrow.
  7. 13. The cells iron is absorbed through
  8. 15. An organ commonly damaged by excessive iron accumulation, potentially leading to chronic disease.
  9. 17. An autoimmune disorder where antibodies attack parietal cells, leading to lack of intrinsic factor and B12 malabsorption is ________ anemia
  10. 18. A common characteristic of secondary hemochromatosis caused by decreased red blood cell production