Hypersensitivity reactions 2025-26

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Across
  1. 4. In Myasthenia gravis autoantibodies against these receptors are formed
  2. 5. This autoimmune disease occurs because of development of autoantibodies against TSH receptor
  3. 7. These are powerful secondary mediators released from activated mast cells that can cause smooth muscle contraction
  4. 8. This condition develops because of molecular mimicry between M protein antigen of Streptococcus and Myosin antigen of cardiac muscle
  5. 11. This is the term referring to genetic predisposition to synthesize inappropriate levels of IgE specific for external allergen
  6. 12. The natural blood group antibodies are also called as ...
  7. 13. Exaggerated immune response to relatively harmless environmental antigens is termed as
  8. 15. This procedure involves repeated intradermal injection of very diluted allergen to make him less sensitive to allergy
  9. 18. Failure of the normal mechanisms of self-tolerance results in reactions against one’s own cells and tissues and it is termed as
  10. 20. IgG antibodies formed by repeated injections of allergen are also called as.... antibodies
  11. 23. This disease characterised by malabsorpton syndrome due to sensitivity to gluten containg food items such as wheat, barley etc.
  12. 24. This procedure involves repeated administration of diluted small amount of allergens
  13. 26. This test is done to diagnose autoimmune hemolytic anemia
  14. 28. This is an incomplete antigen that cannot induce immune response on its own
  15. 29. This is smallest unit of antigenicity
Down
  1. 1. This is the drug of choice in severe type I allergies
  2. 2. This structure comprising of multinucleated giant cells, epitheloid cells, T cells and other cells sorrounding the pathogen is called as
  3. 3. Primary exposure to allergen results in fixing of IgE antibodes to the Fc receptors on mast cells. This phenomenon is called as
  4. 6. This enzyme released from the activated mast cells can be detected within few hours of type I reaction
  5. 9. This is the skin test done to detect type IV allergy to metals like Nickle, Gold etc.
  6. 10. Mismatched blood transfusion will lead to this type of hypersensitivity reaction
  7. 14. severe form of allergy mediated by IgE and degranulation of mast cells is termed as
  8. 16. This is the term that indicates there is a deficiency/decrease in platelet count
  9. 17. Biopsy taken from the indurated lesions in type IV hypesensitivity will show predominance of T cells and ..... cells
  10. 19. Type III hypersensitivity involves deposition of ..... on the tissues
  11. 21. This immunological test is done to measures allergen specific IgE antibodies
  12. 22. This is the primary chemical mediator released by degranulation of mast cells
  13. 25. This condition characterised by butterfly facial rash is an example for type III hypersensitivity reaction
  14. 27. This intradermal skin test is done to know whether a person is exposed to tuberculin antigen previously