ID class MOA

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Across
  1. 2. inhibits DNA and RNA synthesis, selective toxicity to fungi
  2. 5. inhibits 1,3 b-glucan synthesis
  3. 7. mucorales
  4. 10. inhibit protein synthesis; 50S
  5. 12. inhibits 14A sterol demethylase, impairing ergosterol biosynthesis
  6. 16. inhibit protein synthesis 30S
  7. 17. pyrophosphate analogue; noncompetitive inhibitor of viral RNA and DNA polymerase
  8. 18. inhibit endonuclease activity essential for viral gene transcription and replication
  9. 19. inhibits viral DNA synthesis by selective action on infected cells
  10. 21. candida spp. cryptococcus spp.
  11. 22. inhibits bacterial growth without killing
  12. 24. inhibit bacterial DNA gyrase and topoisomerase
  13. 26. kills bacteria
  14. 27. inhibit protein synthesis by binding to ribosomes
Down
  1. 1. inhibit influenza virus, preventing the release and spread of the virus
  2. 3. mold in environment yeast in hostbinds
  3. 4. inhibit bacterial cell wall synthesis
  4. 6. bind to ergosterol, forming pores in membrane
  5. 8. inhibit folic acid synthesis
  6. 9. disrupt cell membrane integrity
  7. 11. inhibit viral DNA synthesis via competitive binding of deoxyguanosine triphosphate
  8. 13. inhibit viral DNA synthesis by competing with ndeoxyguanosine and incorporating in DNA, stopping elongation and replication
  9. 14. inhibit cell wall synthesis
  10. 15. target DNA terminase complex inhibiting DNA processing and packaging
  11. 20. infections caused by fungi such as yeast, molds, and dimorphic fungi
  12. 23. inhibits CMV protein kinase pUL97, preventing phosphorylation of viral proteins
  13. 25. disrupts cell membrane function