IMM Crossword

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Across
  1. 4. large agranulocyte that is phagocytotic; involved in innate immunity
  2. 7. Adaptive immune responses in which there is a major role for effector T cells
  3. 9. An Ig that is expressed on B cell surfaces
  4. 10. The Ag receptor on T cells
  5. 12. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  6. 16. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  7. 18. Family of cytokines that help cells to resist viral infection
  8. 19. the end stage of disease in HIV
  9. 21. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  10. 22. CD4 T cells involved in adaptive immunity
  11. 24. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  12. 25. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  13. 29. Most prevalent granulocyte
  14. 31. Ab
Down
  1. 1. Have granules but aren't as prominent
  2. 2. immune response.
  3. 3. antigen.
  4. 5. Pathogen associated molecular patterns.
  5. 6. A cell that is able to present Ag to T cell receptors on T cells.
  6. 8. protein family that Abs and B cells belong to
  7. 11. WBCs with multi lobed nuclei and cytoplasmic granules
  8. 13. Large granulocyte involved in inducing apoptosis of target cells
  9. 14. A transcription factor that causes tissue specific genes to be transcribed.
  10. 15. Not characterized as granulocytes but do have prominent granules
  11. 17. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand
  12. 20. A type of APC involved in pathogen recognition and activation of immune responses.
  13. 23. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  14. 26. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  15. 27. Differentiate into macrophages
  16. 28. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
  17. 30. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens