IMM Crossword

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Across
  1. 2. Pathogen associated molecular patterns.
  2. 4. The Ag receptor on T cells
  3. 7. large agranulocyte that is phagocytotic; involved in innate immunity
  4. 9. antigen.
  5. 10. CD4 T cells involved in adaptive immunity
  6. 12. Family of cytokines that help cells to resist viral infection
  7. 14. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens
  8. 15. Differentiate into macrophages
  9. 20. Have granules but aren't as prominent
  10. 22. A type of APC involved in pathogen recognition and activation of immune responses.
  11. 23. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  12. 24. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  13. 25. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
  14. 26. Not characterized as granulocytes but do have prominent granules
Down
  1. 1. immune response.
  2. 3. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  3. 4. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  4. 5. A cell that is able to present Ag to T cell receptors on T cells.
  5. 6. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand
  6. 8. A transcription factor that causes tissue specific genes to be transcribed.
  7. 9. Ab
  8. 10. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  9. 11. WBCs with multi lobed nuclei and cytoplasmic granules
  10. 12. protein family that Abs and B cells belong to
  11. 13. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  12. 16. Adaptive immune responses in which there is a major role for effector T cells
  13. 17. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  14. 18. An Ig that is expressed on B cell surfaces
  15. 19. Most prevalent granulocyte
  16. 20. the end stage of disease in HIV
  17. 21. Large granulocyte involved in inducing apoptosis of target cells