immune crossword

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Across
  1. 2. the part of an antibody responsible fro antigen binding, consisting of the light chain and amino-terminal half of the heavy chain disulfide bonded together
  2. 7. adaptive immune response in which there is a major role for effector T Cells
  3. 10. human immunodeficiency virus
  4. 12. a molecule that is recognized in native structure by antibodies or B cell receptor.
  5. 13. general designation of many of the different cytokines
  6. 14. cell. a type of APC that presents antigen in the context of MHC to T cells
  7. 15. cell adhesion molecule
  8. 20. end product of the complement cascade that can kill pathogens directly by forming a pore in pathogen membrane leading to lysis
  9. 22. immune response
  10. 24. slg on B cells that bind Ag and transmit signal 1 to activate B cells
  11. 25. actute protein that binds to phosphocholine
  12. 26. CD* T cells with the effector function of targeting and killing virally infected cells and tumor cells by apoptosis
Down
  1. 1. name of MHC gene complex and proteins in humans
  2. 3. transcription factor expressed in Treg that is needed for Treg cell function
  3. 4. the regions of the antigen binding loops of ig molecules, antibodies and T cells receptors that come into contact with antigen
  4. 5. multiple drug treatment for HIV infection
  5. 6. a mechanism NK cells use to induce apoptosis in virally infected cells or tumor cells
  6. 8. protein family to which antibodies and B-cell receptors belong
  7. 9. cells surface ligands for the leukocyte integrins
  8. 11. the part of the antibody that consists of the carboxy terminal halves of the two heavy chains disulfide bonded to each other
  9. 12. immunoglobulin secreted by plasma cells
  10. 16. presenting cell. a cell that is able to present antigen via MHC molecules to T cell receptos on T cells
  11. 17. family name for cytocines that help cells to resist viral infections
  12. 18. large granular lymphocyte that serves as an innate effector cell by inducing apoptosis of target cells(virally infected cells or tumor cells)
  13. 19. large mononuclear phagocytes that takes residence in many different tissues and organs and contributes to innate immune responses and can act as an effector cell in adaptive immune responses
  14. 21. thymus-derived lymphocyte that are comprised of two different subsets, CD4 T cells and CD8 Tcells
  15. 23. a transcription factor that cause several hundred tissue-specific genes to be transcribed by subpopulation of epithelial cells in the thymus