Viral Pathology

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Across
  1. 5. AKA measles
  2. 6. Acantholytic epithelial cells; may be seen in histologic sections of HSV or pemphigus lesions.
  3. 7. Common oral manifestation of varicella that may precede skin involvement.
  4. 11. These may include lipoatrophy, lipoaccumulation, and premature cardiovascular, kidney, and liver disease.
  5. 13. Oral finding that may be seen in the first stage of measles.
  6. 15. Viral lesion that may cause small, waxy papules with central umbilication on the skin.
  7. 17. Bacterial infection less-commonly associated with HIV infection; treatment requires multidrug therapy.
  8. 18. This condition may mimic hand-foot-and-mouth disease.
  9. 19. Lesions on the tip of the nose indication increased risk for severe ocular infection with herpes zoster.
  10. 21. Giant cells associated with lymphoid tissue during measles infection.
  11. 25. AKA mumps
  12. 30. Virus that causes infectious mononucleosis.
  13. 31. Phase of HIV infection characterized by low CD4+ cell levels and high circulating virus.
  14. 34. A shared characteristic of all human herpesvirus infections.
  15. 35. 80-90% of cases of primary herpes simplex virus infections.
  16. 37. Oral mucosa location of vesicles/ulcers in primary HSV infection.
  17. 38. Classic presentation includes fatigue, high-grade fever, lymphadenopathy, enlarged tonsils, and palatal petechiae.
  18. 39. Herpetic ________ - recurrent HSV on fingers.
  19. 41. Most common deep fungal infection associated with HIV infection.
  20. 42. More than ___% atypical lymphocytes on a peripheral blood smear would support a diagnosis of infectious mononucleosis.
  21. 45. Oral finding that may be seen with rubella.
  22. 46. AKA chicken pox
  23. 48. Enteroviral condition which presents with a small number of 2-4 mm ulcers on the soft palate/tonsillar pillars.
  24. 49. Phase of HIV infection characterized by high viral load and relatively normal CD4+ cell levels.
  25. 50. One of rubella's nicknames.
  26. 51. These types of ulcers may occur more frequently in HIV+ individuals.
  27. 52. Characteristic clinical features of herpes zoster lesions.
  28. 53. Condition that is typically asymptomatic, but when symptomatic, presents with rash that begins on the face/neck.
  29. 54. Gland most often affected by mumps.
  30. 55. Phase of HIV infection with steady decline in CD4+ cell levels and increase in circulating viral levels.
  31. 58. Human herpesvirus genome is composed of double-stranded _____.
  32. 59. Type of glands affected by mumps.
  33. 60. Oral finding frequently affecting the lateral borders of the tongue caused by Epstein-Barr virus in the setting of immunosuppression.
  34. 62. Chronic phase of herpes zoster defined by persistent pain.
  35. 63. Typical treatment for enterovirus infections.
Down
  1. 1. Malignancy caused by HHV-8; rare since the advent of cART.
  2. 2. Systemic antivirals will have therapeutic effect if given within _____ days of symptom onset (onset of vesicles) for primary HSV and herpes zoster.
  3. 3. Enteroviral condition presenting with hyperplastic lymphoid aggregates on the soft palate.
  4. 4. Fungal infection that is often the presenting sign of undiagnosed HIV infection.
  5. 8. AKA shingles
  6. 9. Highly contagious via droplet transmission; 2-week incubation period.
  7. 10. Around 25% of mumps cases.
  8. 12. Involvement of this branch of the trigeminal with HHV-3 increases the risk for blindness.
  9. 14. AKA German measles
  10. 16. AKA "cold sore" or "fever blister"
  11. 20. HIV infected individuals are _____ as likely to develop oral squamous cell carcinoma versus the general population.
  12. 22. These lesions have increased in HIV+ individuals treated with cART.
  13. 23. Antiviral regimen indicated for patients who experience recurrent HSV following dental procedures.
  14. 24. Most common malignancy in individuals who have progressed to AIDS.
  15. 26. Time when systemic antiviral medication is most effective at treating herpes labialis.
  16. 27. Manifestations, including deafness, cardiac abnormalities, and cataracts, in an infant infected in-utero with rubella, especially when infection occurs during the first 12 weeks of gestation.
  17. 28. Enteroviral condition which aptly describes the clinical distribution of its lesions.
  18. 29. May be the first clinical manifestation of HIV, often presenting with petechiae, ecchymosis, or spontaneous gingival hemorrhage.
  19. 32. These viruses typically infect infants/young children and present with mild symptoms or are asymptomatic.
  20. 33. Natural reservoir for HHV.
  21. 36. Where you will find lesions of recurrent herpes simplex virus.
  22. 40. Pattern, distribution, and duration of recurrent HSV lesions in an immunocompromised host.
  23. 43. May represent an unusual pattern of candidiasis in HIV+ individuals.
  24. 44. Most common location for manifestations of recurrent varicella-zoster virus.
  25. 47. Typical treatment for varicella.
  26. 56. ________ and lymphadenopathy may be present in acute herpetic gingivostomatitis.
  27. 57. Type of antifungal therapy indicated in cases of candidiasis with esophageal involvement.
  28. 61. Percent of cases in non-vaccinated individuals that develop measles-associated complications.