Immunology

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Across
  1. 2. Uncontrolled cell death due to damage or disease
  2. 5. T cell surface protein that aids in focusing on MHC molecules
  3. 6. Self-digestive process used by cells during starvation or to present internal antigens in the thymus
  4. 9. Cellular "package" enclosing materials brought into a cell
  5. 10. A primary structure in lymphoid organs for B cell activation
  6. 12. Immune cell type that produces antibodies en masse
  7. 15. Protein that outcompetes CD28 for B7 binding to help shut down immune responses
  8. 17. Essential secondary signal for T cell activation beyond the primary antigen recognition
  9. 19. Inactive state of T cells when proper activation signals are not met
  10. 20. Blood-filtering organ in the immune system
  11. 23. Foreign trigger for an immune defense
  12. 24. Blood vessels that are gateways for lymphocytes into lymph nodes
  13. 26. Cellular structure that shreds misfolded proteins
Down
  1. 1. Starfish-like immune cell essential for T cell activation
  2. 3. Type of T cell that destroys virus-infected cells
  3. 4. Lymphoid tissue associated with mucosal surfaces
  4. 7. The process of eliminating exhausted T cells post-activation
  5. 8. Signaling proteins that guide immune cells to the site of inflammation
  6. 11. Precise target of an antibody on an antigen
  7. 13. Receptor on T cells that inhibits their function when bound by its ligand PD-L1
  8. 14. Immune system's messenger proteins
  9. 16. T cells that produce cytokines like IL-10 to dampen immune responses
  10. 18. Immune system messengers
  11. 21. Active T cells performing their immune duties
  12. 22. Thymic protein that promotes expression of diverse self-antigens for T cell education
  13. 25. Gene important for regulatory T cells that maintain self-tolerance
  14. 27. Cellular self-destruction process