Immunology

Across

1. Tc or Th recognize the antigen presented on surface of APC, stimulates the proliferation of Tc or Th clones and memory cells
3. accumulation of fluid-neutrophils enter site and phagocytose any cell debris or bacteria, 3rd stage of inflammation
5. WBC migrate towards a chemical stimulus
7. immunity that is Antibody mediated (B cells )
8. Inflammation signal that causes cells to migrate to the area, 1st step of phagocytosis
10. plasma-like liquid carried by the lymphatic system
11. also known as Tc cells, Carry out attacks
14. Changes in vasculature-vasoconstriction and calls immune cells to area, 1st stage of inflammation
15. englufed vesicles fuses with vesicle containing digestive fluid, 4th step in phagocytosis
16. Stimulates a primary response and a memory response, Primes the immune system for future exposure to a virulent pathogen.
17. All purpose phagocytic cells that engulf and kills bacteria, it is the primary component of pus.
18. Lives in certain tissue for their whole life ex: Alveolar-lung, dendritic cells- skin, kupffer cells - liver
19. antibodies pass from mother to fetus via placenta: or to infant in her milk
22. Injection of immune serum (Gamma Globulin)
24. monomer in plasma, dimer in mucus, saliva, tears, milk, intestinal secretions, prevents adherence to the epithelia
25. also known as Th cells, secretes interleukins, attracts and stimulates activity of other immune cells, coordination of both cellular and humoral immunity
27. Monomer, 80% circulating, crosses placenta to fetus, 2 degree immune response.
28. develop in the bone marrow
32. debris given off from the cell, 6th step in phagocytosis
34. substance that prompts the generation of antibodies and triggers and immune response
36. bacteria eaten and taken into vesicle, 3rd step in phagocytosis
41. inflammation of the meninges
42. Monomer, B cell membrane antigen receptor
45. Key signs include; redness, warmth, swelling and pain
46. Another word for antibodies, Defensive protein in blood plasma and body secretions:4 polypeptide chains
47. Movement of WBC from the blood into tissue
49. also known as Tm cells, provide immunity from future exposure to antigen
50. 2nd step of phagocytosis, pattern recognition receptors identify and stick to foreign cells
51. Immunity that is cell-mediated ( T cells)

Down

2. Vaccine; dead or attenuated pathogens
4. a network of connecgtive tissues that support cells of the body and provides a passsageway between tissues and organs
6. When reexposed to the same pathogen, the body reacts so quickly that there is no noticeable illness
9. Foreign cells are broken into small pieces, 5th step in phagocytosis
12. Fluid leaks from cells and blood vessels
13. Infection; contact with a pathogen
20. Cell bound antigens (Clumping)
21. filters blood, removes old RBC from circulation, storage site for blood
23. return to healthy tissue, the 4th stage of inflammation
26. Cells of the immune system that digest foreign cells and particles and place pieces of them on their own surfaces in such a way that other cells of the immune system recognize them.
29. small encapsulated, bean-shaped organs, that cluster along lymphatic vessels, theres a high number in the thoracic and abdominal cavities
30. a small gland partly in the neck and partly in the thorax
31. Decreased permeability of the walls of blood vessels in the brain, restricting access to that compartment.
33. Monomer, on mast cells, stimulates release of histamines, attracts eosinophils
35. Pentamer, 10% in plasma, 1 degree immune response
37. Abnormally elevated body temperature.
38. 26 Plasma proteins that work together to destroy bacteria and viruses
39. Immunity directed against a particular pathogen
40. 2nd stage of inflammation vasodilation increase blood flow bring immune components fluid leaks into extracellular area
43. Mature in the thymus
44. - pathogen associated molecular patterns - considered red flags
48. Small protein produced by WBC and tissue cells