Immunology Acronym

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Across
  1. 1. adaptive immune responses in which there is a major role for effector T cells
  2. 4. Repeating patterns on microbes that are recognized by PRRs on immune cells
  3. 5. white blood cells with multi-lobed nuclei and cytoplasmic granules
  4. 6. thymus derived lymphocyte that are comprised of two different subsets CD4 and CD8
  5. 7. a cell wall component of gram negative bacteria which can be bound by TLR-4 on macrophages and dendritic cells.
  6. 9. cell that starts as a monocytes in the blood and tuns into this cell in the interstitial space
  7. 11. designation for a family of cell surface molecules involved in the presentation of peptide antigens to Tcells
  8. 13. autoimmune disease where autoantibodies against DNA, RNA, and proteins associated with nucleic acids) form immune complexes
  9. 14. B lymphocyte that upon activation can differentiate into plasma cells secreting antibody molecules or B memory cells
  10. 15. Regulatory CD4+ cells
  11. 18. general designation of many of the different cytokines, chemical messengers secreted by immune cells that help in their communication with other cells
  12. 20. receptors on immune cells and epithelial cells that recognize and bind PAMPs on microbes
  13. 21. member of TNF receptor family expressed on certain cells that makes them susceptible to being killed by cells expressing the fas ligand
Down
  1. 1. acute phase protein that binds to phosphocholine that can trigger complement activation and acts as a opsonin
  2. 2. protein family to antibodies and B-cell receptors belong
  3. 3. large granular lymphocyte that serves as an innate effector cell by inducing apoptosis of target cells
  4. 6. cells characterized by the cytokines including IL-4; involved in stimulating B cells to produce IgE antibody against helminths
  5. 8. a type of APC that presents antigen in the context of MHC to T cells
  6. 9. soluble acute phase response protein that can bind mannose on pathogens; can activate the lectin pathway of complement and acts as an opsonin
  7. 10. a cell that is able to present an antigen via MHC molecules to Tcell receptors on tcells
  8. 12. multiple drug treatment for HIV infection
  9. 13. an immunoglobulin that is expressed on B cell surface
  10. 16. Receptors on immune cells and epithelial cells that recognize and bind to PAMP's on microbes
  11. 17. the end stage of disease in HIV infection
  12. 19. the AG receptor on Tcells
  13. 22. immunoglobulin secreted by plasma cells