Immunology Acronym Crossword

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Across
  1. 1. A family name for cytokines that help cells combat vital infections
  2. 3. Ag receptor on T cells
  3. 4. Cells A subset of CD4+ cells that are characterized by the cytokines that they produce including IFN gamma involves in activating macrophages and IL-2 involved in promoting CTL responses against intracellular pathogens
  4. 5. Soluble acute phase response to a protein that can bind mannose on pathogens, activate the lectin pathway of complement and acts as a opsonin
  5. 6. A large granular lymphocyte that plays the role of a innate effector cell by causing apoptosis of target cells
  6. 7. The end product of the complement cascade that can kill pathogens directly by forming a pore in the pathogen membrane leading to lysis
  7. 9. Immunoglobulin secreted by plasma cells
  8. 10. Cell adhesion molecule
  9. 11. White blood cells with multi-lobed nuclei and cytoplasmic granules
  10. 14. subset of CD4+ T cells characterized by the cytokines they produce, including IFN- gamma involved in fully activating macrophages, and IL-2 involved in promoting CTL responses against intracellular pathogens
  11. 18. Amino acid sequence in cytoplasmic domains of membrane receptors involves in signal transduction
  12. 20. A T cell subset that is in charge of suppressing a immune response
  13. 23. A cell wall component of gram negative bacteria which can be bound by TLR-4 on macrophages and dendritic cells
  14. 24. Receptors on immune cells and epithelial cells that recognize and bind to PAMPS on microbes
  15. 26. Protein family that antibodies and B-cell receptors belong to
Down
  1. 1. A immune response
  2. 2. Transcription factor that helps to activate the expression of many pro-inflammatory genes
  3. 3. Thymus derived lymphocyte that is comprised of CD4T and CD8 T cells
  4. 4. A cytokine produced by macrophages and T cells that are highly pro inflammatory
  5. 6. A key transcription factor that is required to bind to the IL-2 promoter to cause IL-2 transcription
  6. 8. Repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  7. 12. Designation for a family of surface cell molecules involved in the expression of peptide antigens to T cells
  8. 13. General designation of many of the different cytokines, chemical messengers that are secreted by immune cells that help in their communication with other cells
  9. 15. Name of MHC gene complex and proteins in humans
  10. 16. Autoimmune disease where autoantibodies form immune complexes
  11. 17. Human immunodeficiency virus
  12. 19. A immunoglobulin that is on the surface of B cells
  13. 21. Short DNA sequences flanking Ig and TCR V,D and J gene segments that serve as the binding sites for the RAG complex, allowing Ig and TCR gene rearrangement
  14. 22. A group of pattern recognition receptors that are present on many leukocytes and epithelial cells that recognize PAMPS on pathogens and help initiate immune responses
  15. 25. The two genes essential for Ig and TCR gene rearrangement, their gene products comprise the RAG complex