Immunology Acronyms

5. designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
8. CD8+ T cells with the effector function of targeting and killing virally infected cells and tumor cells by apoptosis
9. acute phase protein that binds to phosphocholine, a constituent of certain bacteria, that can trigger Complement activation and acts as an opsonin
10. a type of APC that presents antigen in the context of MHC to T cells
12. adaptive immune responses in which there is a major role for effector T cells
13. general designation of many of the different cytokines, chemical messengers secreted by immune cells that help in their communication with other cells
15. a cell wall component of gram negative bacteria which can be bound by TLR-4 on macrophages and dendritic cells
17. an immunoglobulin that is expressed on B cell surface
21. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
23. large granular lymphocyte that serves as an innate effector cell by inducing apoptosis of target cells (virally infected cells or tumor cells)
25. white blood cells with multi-lobed nuclei and cytoplasmic granules

1. receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
2. cells surface ligands for the leukocyte integrins; Critical in binding of lymphocytes and other leukocytes to certain cells
3. large mononuclear phagocyte that takes residence in many different tissues and organs and contributes to innate immune responses and can act as an effector cell in adaptive immune responses
4. multiple drug treatment for HIV infection
6. transcription factor that helps activate the expression of many pro-inflammatory genes
7. the Ag receptor on T cells
11. end product of the Complement cascade that can kill pathogens directly by forming a pore in pathogen membrane leading to lysis
14. a key transcription factor that is required to bind to the IL-2 promoter to cause IL-2 transcription
16. thymus-derived lymphocyte that are comprised of two different subsets, CD4 T cells and CD8 T cells
18. a cell that is able to present antigen via MHC molecules to T cell receptors on T cells
19. name of MHC gene complex and proteins in humans
20. family name for cytokines that help cells to resist viral infections; type 1 interferons include IFN-alpha and IFN-beta, as distinguished from IFN-gamma
22. immunoglobulin secreted by plasma cells
24. sIg on B cells that binds Ag and transmits signal 1 to activate B cells