Immunology Crossword

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Across
  1. 3. Autoimmune regulator
  2. 4. Family name for cytokines that help cells to resist viral infections
  3. 6. A mechanism NK cells use to induce
  4. 7. Genes essential for Ig and TCR gene
  5. 9. The part of an antibody responsible for antigen binding
  6. 11. Protein family to which antibodies and B-cell receptors belong
  7. 15. A cell that is able to present antigen via MHC molecules to tcell receptors on T cells
  8. 19. The Ag receptor on T cells
  9. 20. Human immunodeficiency virus
  10. 22. in the presentation of peptide antigens to T cells
  11. 23. A cell wall component of gram negative bacteria which can be bound by TLR-4 on macrophages and dendritic cells
  12. 24. A type of APC that presents antigen in the context of MHC to T cells
  13. 27. Designation for a family of cell surface molecules
  14. 30. The end stage of disease in HIV infection
  15. 31. Acronym for immune response
Down
  1. 1. Receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
  2. 2. A molecule that is recognized in native(original) structure by antibodies
  3. 3. In virally infected cells or tumor cells
  4. 5. B lymphocyte that upon activation can differentiate into plasma cells secreting
  5. 8. Mannose binding lectin
  6. 10. sIg on B cells that binds Ag and transmits signal 1 to activate B cells
  7. 12. Acronym for Membrane attack complex
  8. 13. Multiple drug treatment for HIV infection
  9. 14. Immunoglobulin secreted by plasma cells
  10. 16. Large granular lymphocyte that serves as an innate effector cell by inducing apoptosis of target cells (virally infected cells or tumor cells)
  11. 17. CD8+ T cells with the effector function of targeting and killing virally infected cells and tumor cells by apoptosis
  12. 18. Thymus-derived lymphocyte that are comprised of two different subsets, CD4 T cells and CD8 T cells
  13. 21. molecules or B memory cells
  14. 25. Amino acid sequence in cytoplasmic domains of membrane receptors involved in signal transduction
  15. 26. Acronym for cell adhesion molecule
  16. 28. Adaptive immune responses in which there is a major role for effector T cells
  17. 29. Repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  18. 32. Recombination signal sequences