Immunology Exam 2 Review

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Across
  1. 3. Process in which T cells are selected against if they recognize self peptides presented by MHCs.
  2. 6. Process in which T cells are selected against if they cannot recognize self MHC and peptide complexes.
  3. 7. Organelles which chop up proteins to create peptide fragments in a cell.
  4. 11. Receptor on T cells which can be ligated by B7 to repress T cell activation.
  5. 12. Cells which travel to lymph nodes to provide infection site info.
  6. 13. The membrane protein that binds to helper T cell's co-stimulatory signal in order to help activate the B cell.
  7. 14. Occurs when many BCR's on a B cell surface bind to their epitope.
  8. 15. Coreceptor present on helper T cells.
  9. 16. Compound released in allergic reaction which causes runny nose and watery eyes.
  10. 18. Phenomenon utilized by the TB test.
  11. 22. Prevents endogenous proteins from being loaded into MHC class2 grooves.
  12. 24. T cell which produces IL-17 and IL-21.
  13. 25. Coreceptor present on CTLs.
  14. 26. When the antibody IgG3 creates a bridge between a virus-infected cell and an NK cell to facilitate the target cell's death.
  15. 27. Toll-like receptor which recognizes CpG.
  16. 28. Most important APC during the middle stages of infection.
  17. 30. Loaded into MHC class 1 grooves.
  18. 31. Toll-like receptor which recognizes dsRNA of viruses.
Down
  1. 1. Humans have up to 6 genes that code for this protein.
  2. 2. Loaded into MHC class 2 grooves.
  3. 4. T cell which produces IL-4, IL-5, and IL-13.
  4. 5. Process in which T cells change to become sensitive to Fas ligation and induced to commit suicide.
  5. 8. Works with class switching to create customized and effective B cells.
  6. 9. Location where B cells proliferate rapidly after having been activated.
  7. 10. Most important APC during the ending stages of infection or during reinfection.
  8. 13. The receptor on the helper T cell which ligates the B cell protein CD40 in order to provide the co-stimulatory signal needed for activation.
  9. 17. Toll-like receptor which recognizes LPS.
  10. 19. T cell which produces TNF, IFNg, and IL-2.
  11. 20. State in which immature T cells express both CD4 and CD8.
  12. 21. BCRs are ____ in the cell membrane, whereas antibodies are released into the blood.
  13. 23. The cell type which can provide both the signals needed to activate a T cell.
  14. 29. Process in which cells "eat" their own internal proteins.