Immunology Terms

2. an antibody or other substance which binds to foreign microorganisms or cells making them more susceptible to phagocytosis ex) IgG
4. a molecule that is recognized in native (original) structure by antibodies or
10. a cell wall component of gram negative bacteria which can be boundby TLR-4 on macrophages and dendritic cells
12. Highly active anti-retroviral therapy: multiple drug treatment for HIV infection
14. end stage of disease in an HIV infection
15. natural killer cell; large granular lymphocyte that serves as an innate effector cell
17. transcription factor expressed in Treg cells that is needed for Treg cell function
18. white blood cells with multi-lobed nuclei and cytoplasmic granules
20. a soluble acute phase response protein that can bind mannose on pathogens; can activate the lectin pathway of complement and acts as an opsonin
22. inducing apoptosis of target cells (virally infected cells or tumor cells
23. major histocompatibility complex: molecule that binds peptide fragments derived from pathogens and display them on the cell surface for recognition by the appropriate T cells

1. presenting cell, a cells that is able to present antigen via major histocompatibility complex
3. generalized characterization of many different cytokines aka chemical messengers secreted by immune cells that help in their communication with other cells
5. member of the TNF receptor family expressed on certain cells that makes them susceptible to being killed by cells expressing the Fas ligand
6. a large mononuclear phagocyte that takes residence in many different tissues and organs and contributes to innate immune responses and can act as an effector cell in adaptive immune responses
7. immunoglobulin secreted by plasma cells
8. acute phase protein that binds to phosphocholine (a constituent in some bacterias) that can trigger complement activation and acts as an opsonin
9. end product of the complement cascade cascade that can kill pathogens directly by forming a pore in a pathogen membrane leading to lysis
11. protein family to which antibodies and B-cell receptors belong
13. thymus-derived lymphocytes ex)CD4 and CD8
16. 2 acronyms for the family names of common chemokines (chemicals that are a sub-class of cytokines with cell-attractant properties)
19. cell adhesion molecule; surface protein moderating interactions between cells
21. B lymphocyte that upon activation can differentiate into plasma cells secreting antibody molecules or B memory cells