Infection + Immunity

1. antibiotic that causes mRNA codon to be misread
3. S.aureus strain that is vancomycin-resistant and characterised by its thick cell wall and fewer peptidoglycan cross-links
5. group of human coronaviruses that SARS-CoV2 belongs to
8. when a bacterial population is susceptible to an antibiotic but isn't killed over the treatment duration
13. crucial target for antifungals
15. abbreviation; compound that when added to LPS lowers its charge and prevents colistin interaction
16. antibiotics that interfere with mRNA binding to ribosome
17. broad-spectrum antibiotics that cannot be used against Acinetobacter, Pseudomonas or enterobacteria but is highly effective against mycobacterial infections
18. gene that prevents vancomycin from binding by altering antibiotic binding target
19. antibiotic that blocks polypeptide exit tunnel and prevents peptide elongation
21. last-line treatment option for A.baumanii infections; type of polymyxin

2. antibiotic that binds to 50S + inhibits peptide bond formation
4. antibiotics that prevent bacterial growth
6. antibiotic for M.tuberculosis which likely works by inhibiting arabinogalactan formation
7. abbreviation; bacteria that are non-susceptible to at least 1 agent in all but 2 or less antimicrobial categories
9. antibiotic that interacts with LPS and causes bacterial cell death
10. antibiotics that kill bacteria
11. when the level of activity is more than the addition of the 2 separate activities
12. gene that encodes modified PBP which has low affinity for beta-lactams in MRSA
14. anti-IL6 receptor antagonist typically used for severe rheumatoid arthritis but repurposed for COVID-19
20. amoxicillin is often combined with XXX acid to improve antimicrobial response