Introduction to Migraine

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Across
  1. 4. A multifunctional neurotransmitter released during migraine that causes dilation of cranial blood vessels, activation of inflammatory pathways, and amplification of pain signals
  2. 5. migraine
  3. 7. A class of medications used to treat migraine headaches. Members of this class act as agonists at 5-
  4. 9. Medications that are used to help prevent migraine attacks
  5. 10. (5-HT) receptors in the brain
  6. 12. An exaggerated or abnormally acute sense of smell
  7. 13. Composed of three phases, prodrome (premonitory), headache phase, and postdrome, with each having distinct and sometimes disabling symptoms
  8. 14. Nonexcitable cells of neural tissue that support, protect, and insulate the neurons
  9. 15. Functional junction (or point of close contact) between 2 neurons, or between a neuron and an effector
  10. 17. or brainstem dysfunctions
Down
  1. 1. Headache occurring on less than 15 days per month over the last 3 months, which on some days
  2. 2. on 15 or more days per month for more than 3 months, with migraine headache features on at least 8 days
  3. 3. A phase of migraine that may come before the headache (attack) phase; characterized by visual, sensory,
  4. 6. The part of the brain that includes the hypothalamus and thalamus with the spinal cord and includes the midbrain, pons, and medulla
  5. 8. An unusual intolerance of light that is often experienced by people with migraine
  6. 9. The first phase of migraine, also known as the premonitory phase
  7. 11. A subset of migraine with increased attack frequency and disease burden; defined as headache
  8. 16. month