IPID Acronyms

2. immunoglobulin secreted by plasma cells
3. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
4. adaptive immune responses in which there is a major role for effector T cells
7. transcription factor that helps activate the expression of many pro-inflammatory genes
9. name of MHC gene complex and proteins in humans
10. end product of the Complement cascade that can kill pathogens directly by forming a pore in pathogen membrane leading to lysis
11. acute phase protein that binds to phosphocholine, a constituent of certain bacteria, that can trigger Complement activation and acts as an opsonin
12. the Ag receptor on T cells
13. a cell wall component of gram negative bacteria which can be bound by TLR-4 on macrophages and dendritic cells
14. general designation of many of the different cytokines, chemical messengers secreted by immune cells that help in their communication with other cells
15. Pattern recognition receptors: receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes

1. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
2. a cell that is able to present antigen via MHC molecules to T cell receptors on T cells
5. cells surface ligands for the leukocyte integrins; Critical in binding of lymphocytes and other leukocytes to certain cells
6. family name for cytokines that help cells to resist viral infections
7. large granular lymphocyte that serves as an innate effector cell by inducing apoptosis of target cells (virally infected cells or tumor cells)
8. sIg on B cells that binds Ag and transmits signal 1 to activate B cells.
9. multiple drug treatment for HIV infection
12. a family of Pattern Recognition Receptors present on many leukocytes and epithelial cells that recognize PAMPs on pathogens and help initiate immune responses
14. protein family to which antibodies and B-cell receptors belong