KEY TERMS

3. The process where osteoclasts breakdown old bone releasing calcium and phosphate into the blood. It leads to a decrease in bone mass and bone density (two words)
4. These are laboratory-made drugs that are designed to serve as substitute antibodies to target immature osteoclasts and decrease bone resorption. (three words)
7. Specialized cells that form bone. They synthesize collagen and other substances that help create bone matrix.
8. The continuous process in which old bone is resorbed and new bone is formed. (two words)
10. Specialized cells that breakdown old bone in the process of bone resorption.

1. Bone-modifying drugs that prevent loss of calcium and increase bone density by moving blood calcium into the bone, binding to calcium in the bone, and preventing osteoclasts from destroying bone cells and resorbing calcium.
2. Normally produced by specialized cells in the thyroid gland. It decreases bone resorption by the osteoclasts.
5. These drugs are used for patients at high risk for fracture. They help increase activity of osteoblasts resulting in formation of new bone. (two words)
6. The gradual loss of bone density and strength, which leads to spinal shortening and increased risk for bone fractures.
9. The most common cells in bone that help regulate bone remodeling and bone resorption.
11. used to treat osteoporosis act by activating estrogen effects on bone tissue (decreasing bone resorption and increasing bone density) while blocking estrogen effects on the breast and the uterine tissue. (abbreviation)