L4 CCBs: Mechanism of Action of CCBs

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Across
  1. 6. Chronotropy Effect of CCBs on heart rate
  2. 8. Ions Ions that CCBs block from entering smooth muscle and myocardial cells
  3. 9. The primary effect of CCBs on arterial smooth muscle
  4. 11. Inhibits calcium influx through L-type calcium channels leading to vasodilation
  5. 12. Node CCBs slow conduction through this part of the heart
  6. 13. The tissue where CCBs like Verapamil exert their strongest effect
  7. 14. Channel The specific calcium channel blocked by CCBs
  8. 15. Inotropy Effect of CCBs on cardiac contractility
Down
  1. 1. Primarily reduces heart contractility and slows AV node conduction
  2. 2. CCBs are commonly used to treat this condition due to their effect on blood pressure
  3. 3. Cells Cells in the SA node affected by CCBs leading to a slower heart rate
  4. 4. Muscle Type of muscle CCBs primarily affect in blood vessels
  5. 5. A calcium channel blocker that has intermediate effects on both heart rate and vasodilation
  6. 7. Condition where CCBs can be used to relieve narrowing of coronary arteries
  7. 10. The blood vessels most affected by CCBs leading to decreased blood pressure