Lecture 2 RNA #2

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Across
  1. 4. — Why waste good coding when the same message can be edited more than one way?
  2. 5. — Stop lying! Without proper ends, your transcript may not survive the trip out.
  3. 8. — At first TATA keeps me close; later I travel with the polymerase.
  4. 12. — Eight proteins provide somewhere for all that negativity to wrap itself around.
  5. 14. — Happily lives in a travelling bubble, and this is where much of the action happens.
  6. 16. — An enzyme in the removal business that likes to keep things tight and tidy.
  7. 18. — Three would be too many for this box.
  8. 20. — Complicated in hundreds of ways, absolutely necessary for things to properly begin.
  9. 21. — A naturally derived way of making Rho lose its ability to call it quits.
  10. 22. — +1 has nothing to do with your final grade.
  11. 23. — Put this on and relax.
  12. 26. — A region of DNA where getting everyone together is more important than producing anything yet.
  13. 28. — A protein whose name leaves very little mystery about which box it prefers.
  14. 30. — RNA is wiggly enough to make one of these and convince polymerase to pause.
  15. 31. — CUT across the single-ring members of this family.
  16. 33. — Unlike my deoxy relative, I kept what was mine at carbon number two.
  17. 34. — A non-academic process that awards approximately 200 As.
  18. 35. — The first ribonucleotide bond means we've finally moved beyond all that preparation.
Down
  1. 1. — A dog may wag one, but an RNA molecule needs one for stability and export.
  2. 2. — Bacteria don't have much to lose, but eukaryotes need this to help get the final message ready.
  3. 3. — At one end of the message I enter into an unusual 5′–5′ relationship.
  4. 5. — Twenty-three can make slipping off considerably less likely.
  5. 6. — Starting over and over while leaving little messages behind.
  6. 7. — Likes a transcript rich in C's, but bicyclomycin would rather it didn't finish the job.
  7. 9. — A transcriptional boost that may need DNA to bend over backwards to do its job.
  8. 10. — Merely a stop signal, not an Arnold Schwarzenegger movie.
  9. 11. — Whether I deserve this name depends entirely on whether they decide to cut me out.
  10. 13. — Not every protein invited to the regulatory performance wants the show to go on.
  11. 15. — RNA pol II has a rather important job to get done.
  12. 17. — A lead actor that can help turn up the performance without standing right beside the stage.
  13. 19. — Capped, tailed and processed; now the message finally has a new name.
  14. 24. — Up to 165 of these little failures may accompany one productive success in a prokaryote.
  15. 25. — RNA decided it could live without T.
  16. 27. — An octomeric protein package with tails that are open to modification.
  17. 28. — Sounds like the second edition, and carries the protein that knows where TATA is.
  18. 29. — An amino acid enriched in histone tails; acetylation makes me not quite so positive anymore.
  19. 32. — One RNA's version of me may be another RNA's intron.