Micturition reflex - control of normal bladder filling and emptying

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Across
  1. 2. brainstem location of the micturition centre that coordinates voiding
  2. 6. eponymous name for the pontine micturition nucleus
  3. 9. somatic nerve giving voluntary control of the external urethral sphincter
  4. 11. autonomic division dominant during storage (detrusor relaxes, internal sphincter contracts)
  5. 13. type of feedback by which detrusor contraction increases stretch and strengthens contraction
  6. 14. type of receptor in the detrusor that senses bladder filling
  7. 16. smooth muscle of the bladder wall that contracts to expel urine during voiding
  8. 17. phase in which the bladder empties
Down
  1. 1. involuntary (smooth muscle) urethral sphincter, controlled by the autonomic system
  2. 3. voluntary (skeletal muscle) urethral sphincter, controlled by the pudendal nerve
  3. 4. acetylcholine receptor type at the external sphincter neuromuscular junction
  4. 5. lobe (medial prefrontal/anterior cingulate) that inhibits the PMC to delay voiding
  5. 7. direction of the sensory signals travelling via the pelvic nerve to S2–S4
  6. 8. autonomic division dominant during voiding
  7. 10. voluntary holding of urine, maintained by cortical inhibition of the PMC
  8. 12. sympathetic nerve driving the storage phase
  9. 14. phase in which the bladder fills while remaining at low pressure
  10. 15. parasympathetic nerve (S2–S4) driving detrusor contraction and voiding