MOCK-UP for example only

1234567891011121314151617181920212223242526272829303132333435363738394041
Across
  1. 5. The reversible pause in embryonic development used by species including bears, killifish, and marsupials to wait for better conditions, whose molecular mechanisms are studied by the Pauli lab at the IMP
  2. 6. The international song contest whose Vienna staging forced a complete rescheduling of a Vienna BioCenter scientific conference after every hotel room in the city was booked
  3. 8. Visual design element created by algorithmically mirroring and tessellating microscopy images submitted by research groups at IMBA and the IMP
  4. 9. The category of disease that can result from mutations in FOXP3, the master protein studied by the van der Veeken lab at the IMP that keeps the immune system from attacking the body’s own tissues
  5. 13. The platform launched in March 2025 by the Vienna BioCenter that grew to nearly 1000 members within months, connecting former researchers with current students for career guidance
  6. 14. IMP group leader who investigates the mechanical and chemical forces that drive cells to self-organize into the right shapes during the earliest stages of embryonic development
  7. 19. Founding scientific director of the IMP who recruited its first group leaders and initiated the partnership with the University of Vienna that gave rise to the Vienna BioCenter
  8. 25. IMP scientific director whose lab discovered that the protein cohesin organizes the genome by reeling DNA into loops, a mechanism now recognized as fundamental across all kingdoms of life
  9. 26. IMP senior group leader whose lab studies how cells mark unwanted proteins for destruction, with implications for developing new antibiotics and understanding muscle disease
  10. 28. The TV drama that the IMP’s first generation of PhD students and postdocs watched together at five o’clock each day before returning to the labs (two words)
  11. 29. Computational scientist who completed three collaborative publications during a one-year visiting stay at the IMP in 2024, making machine learning tools accessible to experimental researchers
  12. 31. Biannual award for cancer research, won by IMP scientists in both 1988 (Hartmut Beug) and 2025 (Anna Obenauf)
  13. 33. The electronics company whose former factory in St. Marx was converted in 1988 into the IMP’s first laboratory building
  14. 34. The earliest stage of human development that the Pinheiro lab recreates in the lab using stem cells, to study how the protective membrane surrounding it builds its distinct structure
  15. 35. The compartment inside every cell that acts as a gatekeeper between the DNA blueprint and the protein-making machinery, and whose molecular gates the Plaschka lab at the IMP studies by investigating how messenger RNA passes through them
  16. 36. The tissue whose proteins are studied by the Clausen lab at the IMP to understand how disease-associated mutations lead to dysfunction and premature aging
  17. 37. Joint group leader at IMBA and the IMP whose cryo-electron tomography partnership with the Brennecke lab produced a landmark paper in the journal Cell in 2025
  18. 38. IMP senior group leader whose lab developed CaTCHseq, a platform that traces in real time how tumors develop resistance to treatment and how cancer cells learn to evade immune attack
  19. 39. The fundamental process by which a cell reads its DNA to produce RNA, whose control by enhancers and other regulatory sequences is decoded by the Stark lab at the IMP using a combination of experiments and artificial intelligence
  20. 40. IMP group leader whose lab builds new microscopes and develops the mathematical methods that allow individual molecules to be tracked inside living cells with nanometer precision
  21. 41. The number of countries represented among the roughly 255 researchers at the IMP in 2025
Down
  1. 1. One of the theatrical formats the Vienna BioCenter Amateur Dramatic Club has staged on campus since 2008, alongside rehearsed readings with visiting playwrights
  2. 2. The model organism maintained by a Vienna BioCenter resource center whose fly stocks support between 400 and 500 publications per year
  3. 3. A jumping gene that can copy and reinsert itself throughout the genome, posing a constant threat to genome stability that the Klumpe lab at the IMP investigates in fruit fly germline cells
  4. 4. Annual prize for early-career researchers, established in memory of a former IMP PhD student
  5. 7. The molecular tag attached to damaged or unwanted proteins to mark them for recycling, whose chain structures and signals are studied by the Haselbach lab at the IMP
  6. 10. The scale at which the Balzarotti lab works, using DNA barcoding techniques that assign each target a unique code, allowing dozens of different molecular species to be mapped simultaneously at nanometer resolution
  7. 11. IMP senior group leader whose lab combined AI-based protein structure prediction with experiments to identify the protein complex behind the first molecular contact between sperm and egg, described as the kiss of life
  8. 12. A disease-causing organism whose DNA, when detected floating in the cell’s interior rather than safely stored in the nucleus, triggers a powerful immune alarm studied by the Gaidt lab at the IMP
  9. 15. IMP senior group leader whose lab designs rational drug combinations that target the specific vulnerabilities of cancer cells, with the goal of preventing tumors from adapting and developing resistance to treatment
  10. 16. IMP group leader whose lab investigates how molecular machines package and export messenger RNA from the cell nucleus to the site of protein production
  11. 17. The number of research groups at the IMP in its 40th year, working across fields from neurobiology to cancer research
  12. 18. IMP group leader who discovered that mammals, like plants and bacteria, use a sensing mechanism called Effector-Triggered Immunity to detect and respond to the activities of invading pathogens
  13. 20. IMP group leader whose cryo-electron microscopy technology platform studies how the proteasome adapts its structure to meet the cell’s changing needs
  14. 21. The ability of tumor cells to survive treatment by rewiring their signaling pathways and manipulating the immune system, and the central problem that the Obenauf lab at the IMP works to understand and overcome
  15. 22. IMP senior group leader whose lab developed DeepSTARR, a neural network that predicts how DNA sequences control gene activity, enabling the design of entirely synthetic enhancers
  16. 23. The strength that researchers develop through repeated setbacks, often invisible to the people who have developed it, but present in almost every scientific career
  17. 24. The AI research institute co-founded at the Vienna BioCenter in September 2024 to make artificial intelligence a partner in generating scientific hypotheses
  18. 27. The gene-editing technology used by the Zuber lab at the IMP to run large-scale screens that reveal which genes cancer cells depend on to survive
  19. 30. IMP group leader whose lab engineers mouse models to study how regulatory T cells maintain immune balance, preventing the body from attacking its own healthy tissues (three words)
  20. 32. The structure that packages DNA in the cell nucleus, whose abnormal organization when cohesin is defective can contribute to cancer and birth defects, according to research from the Peters lab at the IMP