Module 8 Crossword

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Across
  1. 2. Non‑replicating vaccine prepared from killed pathogen
  2. 4. Immune detection and elimination of transformed cells
  3. 6. Secondary immunisation enhancing immune memory
  4. 9. Tumour strategies to avoid immune recognition
  5. 10. Spread of tumour cells to distant tissues
  6. 12. Inhibitory pathway regulating T‑cell activation
  7. 13. Selection of higher‑affinity lymphocyte clones
  8. 14. Live vaccine with reduced pathogenicity
Down
  1. 1. Strength of antigen–antibody binding
  2. 2. Cancer treatment using immune mechanisms
  3. 3. Long‑term persistence of antigen‑specific lymphocytes
  4. 5. Novel tumour‑specific antigen arising from mutation
  5. 7. Induction of protective immunity without disease
  6. 8. Referring to determinants recognised by the immune system
  7. 11. Vaccine component enhancing immune activation