Mutations - Molecular Genetics

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Across
  1. 4. A type of mutation that has no effect on the protein synthesized (specify where they may occur)
  2. 8. The most common type of mutation since 90% of our DNA is non-coding
  3. 9. Mutation leaves the organism unaffected, leads to an extra chromosome copy
  4. 14. Mutation that substitutes a stop codon for an amino acid (interpret the effects of this mutation on the cell and polypeptide chain)
  5. 15. mutations that lead to amino acid substitution (Interpret the effects of this type of mutation)
  6. 16. an inversion mutation leads to the reversal of ---- that may lead to disrupted gene function
  7. 17. results when a DNA sequence is reversed.
  8. 18. edits made to a chromosome
  9. 20. Mutation leading to segment dislocation between chromosomes, causing faulty protein synthesis
  10. 21. external mutation causing agents (list examples)
  11. 22. Mutations that cause multiple missense or nonsense mutations, leading to a non-functioning protein
Down
  1. 1. The study of genomes and the relationship of genes between species
  2. 2. results from the replacement of a nucleotide, potentially changing the amino acid codon
  3. 3. Large scale mutations involving multiple nucleotides, genes, or regions of a chromosome; identifiable in karyotype.
  4. 5. Naturally caused mutations that are often a result of faulty DNA replication
  5. 6. these type of mutations occur in alleles and are not noticeable in an organism's karyotype
  6. 7. aka jumping genes
  7. 10. non coding regions aka VNTRs (list full form
  8. 11. Mutations as a result of a change in the number of nucleotides, changes the whole coding of the sequence
  9. 12. Results when two adjacent nucleotides trade places
  10. 13. used in paternity tests and forensics (write full form and type of mutation on the back of page)
  11. 19. mutations occurring in a single nucleotide