Neurodevelopment Crossword

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Across
  1. 4. The resulting portion of neuroectoderm formed during development after the thickening of the trilaminar disc, made possible through specific signaling molecules released by the notochord
  2. 5. The bordering tissue of the neural plate that gives rise to the peripheral nervous system
  3. 6. The process that encourages the growth cone of one neuron to grow towards a specific target due to the secretion of membrane-bound chemoattractive cues
  4. 7. The process by which a neuronal stem cell divides to produce two daughter cells; both neuronal stem cells and differentiated cells can be produced
  5. 12. The order in which the layers of cells are developed in the cerebral cortex
  6. 14. Portion of the neuron located at the end of a neurite seeking a synaptic target; this element of the neuron detects and selectively identifies molecular signals within the environment in the efforts of pursuing a synaptic partner
  7. 16. Collective term for the axons and dendrites of a neuron
  8. 18. A specialized region of the mesoderm which provides signaling cues during embryonic development, particularly during the formation of the neural plate
  9. 19. The membrane-bound guidance molecule secreted that selectively discourages a growth cone from growing towards a target, thereby repelling the growth cone from the incorrect target
  10. 20. The innermost layer of the trilaminar disc; most of the cells in the nervous system are derived from this tissue
  11. 21. Neurons are born in and migrate from this location to their intended layer of the cerebral cortex, by way of radial glia
  12. 22. A type of neural cell that can only complete a limited number of cell division cycles, thus limiting the capability of neurons in the brain to divide and create new neurons
Down
  1. 1. This feature of the cerebral cortex allows for the specific organization of cells within the cortex; cortical cells travel through this inside-out “scaffolding” with the help of radial glia
  2. 2. The type of stem cell division resulting in either two daughter stem cells or two daughter differentiated cells
  3. 3. The membrane-bound guidance molecule secreted that selectively encourages a growth cone to grow towards a target, thereby drawing the growth cone towards the correct target
  4. 8. Function in neurodevelopment to provide transportation for cells forming the specialized layers of the cerebral cortex
  5. 9. The process by which the neural plate folds in on itself, forming the neural tube and the elementary construction of the central and peripheral nervous system
  6. 10. The process that discourages the growth cone from growing towards a specific target due to the secretion of membrane-bound chemorepulsive cues
  7. 11. The process in which new neurons are produced or “born”
  8. 13. Process that occurs within the cerebral cortex, as neurons born in the ventricular zone must relocate to their intended cortical layer; radial glial cells aid in this process
  9. 15. The formation that arises when the neural plate involutes, a process known as neurulation; this formation gives rise to the central nervous system
  10. 17. The type of stem cell division resulting in two daughter cells, one of which is another stem cell, and the other a differentiated cell