Neurotransmitter

2. Promote wakefulness and appetite.
7. Inhibition of this receptor relieves nausea and vomiting but causes hyperprolactinemia.
11. Secreted by endothelium to induce vascular smooth muscle contraction
14. Pain, vasodilation and cough !!!
16. Learning and memory. Elevated levels relieve Alzheimer's disease.
17. Activate guanylate cyclase to relax smooth muscle cells.
18. Neuropeptide that triggers nausea/vomiting

1. Excess amount leads to tremor and palpitation.
3. Excess leads to cytotoxicity. Play a role in learning and memory.
4. Elevate blood pressure and water retention.
5. Pain reliever with euphoria
6. Its activation induces severe airway tightening and wheezing.
8. A primary endogenous vasopressor that activates as a potent alpha 1, alpha 2, and beta 1 adrenergic agonist, but minimal effect on beta 2 receptors.
9. Synthesize in the adrenal medulla
10. Trigger platelet aggregation to seal the wound
12. Activation increases gastric acid secretion while inhibition prevents motion sickness.
13. Retrograde signaling
15. Locally made messengers that turn up the heat and the hurt.