Nobel laureates and their discoveries

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Across
  1. 2. Martin Chalfie discovered ___; commonly used as a fluorescent probe
  2. 6. Jeffrey C. Hall discovered this cycle which modulates timings for waking up and sleeping____(two words)
  3. 8. H. Robert Horvitz discovered ____ a mode of regulated cell death
  4. 10. Wilhelm Conrad Röntgen discovered ____; an electromagnetic wave used to image bones structures
  5. 11. Harold Varmus discovered ___ are genes responsible for some cancers
  6. 13. Harvey J. Alter discovered this virus ___(one word & one letter)
  7. 15. Elizabeth H. Blackburn discovered ____ is responsible for conserving ends of DNA
  8. 16. Daniel Nathans discovered____ that can cleave DNA
  9. 18. Craig C. Mello discovered this mechanism of transcriptional or translational silencing
  10. 20. Robert Edwards discovered this therapy to fuse a sperm and egg ex-vivo called ___(three words)
Down
  1. 1. Bruce A. Beutler discovered this property of the human immune system(two words)
  2. 3. Shinya Yamanaka discovered how to reprogram any cell to ____(three words)
  3. 4. Paul Lauterbur discovered___; commonly used for brain imaging
  4. 5. Françoise Barré-Sinoussi discovered this virus
  5. 7. Ferid Murad studied the effect of ___ (two words) on the cardiac system
  6. 9. Yoshinori Ohsumi discovered___ a mechanism of degradation of the cell that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism.
  7. 12. Venkatraman Ramakrishnan did his studies on the structure of the ____
  8. 14. Jennifer Doudna discovered___ used for gene editing
  9. 17. Tu Youyou found a novel cure for ___
  10. 19. Alfred G. Gilman did his work on the significance of _____(one letter & one word)