Non-Biological DMARDs

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Across
  1. 3. Name for all drugs that bind to receptors and produce pharmacological response
  2. 4. Volume of blood cleared of drug per unit of time
  3. 8. This cytochrome P450 beauty metabolises more than 50% of drugs
  4. 9. The mechanism by which a drug brings about action
  5. 12. Important to lipid solubility
  6. 13. Most common reaction of Phase 1 metabolism
  7. 15. Not really a drug for athletes only!
  8. 16. A factor that is associated with hepatic function
Down
  1. 1. What the drug does to the body
  2. 2. The drug becomes a different chemical via liver
  3. 5. Amount of drug reaching systemic circulation in tact
  4. 6. Name for all drugs that bind to receptors but do not produce a pharmacological response
  5. 7. Abbreviation for amount of drug that is extracted by liver
  6. 9. pH at which 50% ionised and 50% unionised
  7. 10. A process of phase 2 metabolism
  8. 11. Most common way a drug crosses cell membranes
  9. 14. The four main parts to what the body does to the drug