Osteoporosis

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Across
  1. 2. T scores between -1.0 and -2.5
  2. 3. a standard measurement for measuring bone density
  3. 4. thyroid risk factor
  4. 6. Repeat measures of bone density every 1-2 years after starting _______.
  5. 9. Daily requirement of 1,000 – 1,500 mg in divided doses with meals
  6. 14. Lab measurement for secondary causes of osteoporosis (parathyroid hormone, TSH, 25-hydroxyvitamin D
  7. 15. Alendronate, Risedronate, ibandroante
  8. 20. Best locations for measuring bone density
  9. 21. Sensitive screening test for above
  10. 23. The lifetime risk of a hip fracture in a woman with T-score of 0
  11. 25. Related to the GI tract
  12. 26. SERM FDA approved for prevention and treatment of osteoporosis
  13. 27. subcutaneous injection daily for osteoporosis
  14. 29. Severe side effect of medications above, higher in patients with cancer receiving IV version
  15. 33. Medication risk factor
  16. 36. lab evaluation for secondary osteoporosis (calcium, phosphorus, albumin, alkaline phosphatase
  17. 37. 50% of women with_____ fractures are unable to walk independently after their fracture heals.
Down
  1. 1. Prolonged premenopausal ______ (risk factor)
  2. 5. 800 _______ of vitamin D daily
  3. 7. 50% of _______ older than 50 years will experience an osteoporotic fracture
  4. 8. Activity resulting in a 5-10% reduction in bone density
  5. 10. a measurement for bone density compared to people of the same age
  6. 11. ________ less than 127lbs (risk factor)
  7. 12. Exercise important for increasing bone mineral density
  8. 13. offered to women without preexisting fractures and T-score <-2.0, women with T-score -1.5 and another clinical risk factor, and women with prior osteoporotic fractures
  9. 16. A monoclonal antibody against _____, denosumab (Prolia)
  10. 17. Women older than ________ should have a bone mineral density test.
  11. 18. IV medication given yearly
  12. 19. Chronic daily use above 7.5mg prednisone or equivalent associated with bone loss
  13. 22. duel-energy x-ray ________
  14. 24. Risk factor for osteoporosis
  15. 28. ___________ history of a hip fracture (risk factor)
  16. 30. A disease of the bone characterized by a predisposition to low-trauma fracture caused by low bone mass and disordered microarchitecture.
  17. 31. 200 IU daily nasal spray for treatment of osteoporosis
  18. 32. disordered mineralization of newly formed bone protein matrix, associated with low serum phosphate and elevated serum alkaline phosphatase
  19. 34. Disease associated with chronic malabsorption occurring in ~1% Caucasian women
  20. 35. Deficiency associated with hypophosphatemia and hypocalcemia