Osteoporosis

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Across
  1. 1. Disease associated with chronic malabsorption occurring in ~1% Caucasian women
  2. 3. ___________ history of a hip fracture (risk factor)
  3. 8. disordered mineralization of newly formed bone protein matrix, associated with low serum phosphate and elevated serum alkaline phosphatase
  4. 10. T scores between -1.0 and -2.5
  5. 11. Activity resulting in a 5-10% reduction in bone density
  6. 12. A monoclonal antibody against _____, denosumab (Prolia)
  7. 15. Medication risk factor
  8. 16. Alendronate, Risedronate, ibandroante
  9. 18. offered to women without preexisting fractures and T-score <-2.0, women with T-score -1.5 and another clinical risk factor, and women with prior osteoporotic fractures
  10. 22. The lifetime risk of a hip fracture in a woman with T-score of 0
  11. 23. Sensitive screening test for above
  12. 29. 50% of _______ older than 50 years will experience an osteoporotic fracture
  13. 30. Repeat measures of bone density every 1-2 years after starting _______.
  14. 31. ________ less than 127lbs (risk factor)
  15. 32. lab evaluation for secondary osteoporosis (calcium, phosphorus, albumin, alkaline phosphatase
  16. 34. A disease of the bone characterized by a predisposition to low-trauma fracture caused by low bone mass and disordered microarchitecture.
  17. 35. Women older than ________ should have a bone mineral density test.
  18. 36. Deficiency associated with hypophosphatemia and hypocalcemia
Down
  1. 1. Chronic daily use above 7.5mg prednisone or equivalent associated with bone loss
  2. 2. 200 IU daily nasal spray for treatment of osteoporosis
  3. 4. a standard measurement for measuring bone density
  4. 5. Risk factor for osteoporosis
  5. 6. a measurement for bone density compared to people of the same age
  6. 7. IV medication given yearly
  7. 9. Best locations for measuring bone density
  8. 13. 50% of women with_____ fractures are unable to walk independently after their fracture heals.
  9. 14. Exercise important for increasing bone mineral density
  10. 17. Daily requirement of 1,000 – 1,500 mg in divided doses with meals
  11. 19. thyroid risk factor
  12. 20. Prolonged premenopausal ______ (risk factor)
  13. 21. Related to the GI tract
  14. 24. 800 _______ of vitamin D daily
  15. 25. Severe side effect of medications above, higher in patients with cancer receiving IV version
  16. 26. duel-energy x-ray ________
  17. 27. subcutaneous injection daily for osteoporosis
  18. 28. Lab measurement for secondary causes of osteoporosis (parathyroid hormone, TSH, 25-hydroxyvitamin D
  19. 33. SERM FDA approved for prevention and treatment of osteoporosis