Path & Disease Exam 2

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Across
  1. 2. A passive decrease in blood flow; may be acute or chronic.
  2. 5. (2 words) Type 3 Hypersensitivity; due to formation of antigen-antibody complexes that activate complement. Often mistaken for Type 2, but requires a SOLUBLE antigen.
  3. 6. Arterioles, capillaries, and venuoles. Tiny blood vessels.
  4. 8. Type 1 Hypersensitivity; requires a sensitization phase. Mediated by IgE.
  5. 13. The failure of the immune system to protect host from infectious organisms or development of cancer.
  6. 17. A type of immune cell that originates within the bone marrow, but may mature either in the bone marrow or in the thymus.
  7. 18. The primary hemostatic pathway initiated by exposure of blood to coagulation factors found on perivascular cells. Requires coagulation factors VII and III.
  8. 19. ___ Thrombocytopathia is a failure of platelets to function due to a problem with the factors required for normal functions.
  9. 20. Protection against microbes/infections.
  10. 21. ___ Immunity is acquired, specific, and has memory; the basis for immunization/vaccines.
  11. 23. Failure of blood clotting, often due to abnormal function or integrity of coagulation factors.
  12. 25. ___ Thrombocytopathia is a failure of platelets to function due to the platelets themselves.
  13. 26. The primary hemostatic pathway often considered the "work-horse." Requires coagulation factors XII, XI, IX, and VIII.
Down
  1. 1. ___ Immunity, considered natural or native, is non-specific and lacks memory. First line of defense.
  2. 2. (2 words) The volume of blood pumped by the heart per minute.
  3. 3. Type 2 Hypersensitivity; results in destruction or alteration of target cell. Mediated by IgG and IgM.
  4. 4. A collection of blood within the capillaries, due to increased metabolic activity or acute inflammation. Active process.
  5. 7. The primary hemostatic pathway responsible for fibrin formation. Requires coagulation factors X, II, I, and XIII.
  6. 9. Abnormal distribution of fluid in the body, often caused by increased microvascular permeability. Clinical signs depend on the location and extent of occurance.
  7. 10. A decrease in the concentration or function of coagulation factors, either inherited or acquired.
  8. 11. Removal of the hemostatic plug by plasmin.
  9. 12. ___ Circulation: Capable of storing up to 65% of blood in the body. Low resistance pathway for return of blood to the heart.
  10. 14. (Hyphenated) Type 4 Hypersensitivity; requires T-cells, not antibody-dependent.
  11. 15. ___ Circulation: Carries blood away from the heart; facilitate rapid blood flow with minimal resistance.
  12. 16. An inappropriate or misdirected response by the immune system towards a foreign or self antigen.
  13. 22. The highly regulated processes that maintain blood in the body.
  14. 24. ___ Circulation: Blind-ended capillaries that permeate tissues surrounding microcirculatory structures.