Pathways and Puzzles

1234567891011121314151617181920
Across
  1. 4. hydrolyze phosphorylated proteins
  2. 5. in the absence of insulin, the recptor exists as a ___
  3. 6. signal molecule
  4. 7. number of helices in GPCRs
  5. 12. small G proteins are ___, as opposed to being heterotrimeric
  6. 13. hormone released by ß cells of the pancreas
  7. 16. enzyme responsible for increasing cAMP concentration
  8. 17. refers to the state of the unactivated G protein
  9. 19. hormone that binds to the ß-adrenergic receptor
  10. 20. in Cholera, the G protein is constitutively ___
Down
  1. 1. enzyme that converts cAMP to AMP
  2. 2. molecules that relay info. from the receptor-ligand complex
  3. 3. ____ syndrome: diseases resulting from a mutation leading to a constitutively active form of PKA, resulting in excess cortisol secretion
  4. 8. family of proteins that calmodulin belongs to, consisting of a helix-loop-helix motif
  5. 9. stimulus that triggers the release of the signal molecule
  6. 10. number of calcium binding sites in calmodulin
  7. 11. one of the residues phosphorylated by PKA
  8. 14. calcium sensor in eukaryotic cells
  9. 15. number of regulatory units bound to enzymatically active form of PKA
  10. 18. second messenger that activates PKC