Perinatal and Congenital Infections Crossword

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Across
  1. 3. Intravenous antiviral given for 14 days (for skin/eye/mouth disease) or 21 days (for CNS/disseminated disease) to treat neonatal Herpes Simplex Virus
  2. 7. Vitamin supplement co-administered at 5–10 mg/day with Isoniazid (INH) prophylaxis to prevent neurological side effects
  3. 9. Antimicrobial used alongside sulphadiazine and folinic acid for 12 months to treat a confirmed congenital toxoplasmosis infection
  4. 11. Specific type of penicillin (50,000 units/kg) given as a single intramuscular injection when congenital syphilis is deemed "less likely" or "unlikely"
  5. 12. Routine quantitative serological test evaluated in the infant's serum (not cord blood) to assess for congenital syphilis
Down
  1. 1. Preferred oral antiviral used for 6 months to treat moderate-to-severe symptomatic congenital Cytomegalovirus (CMV) infection
  2. 2. Antiretroviral drug paired with Nevirapine and given twice daily for high-risk HIV-exposed infants
  3. 4. Prophylaxis started at 4–6 weeks of age for all HIV-exposed infants and continued until HIV infection can be definitively excluded
  4. 5. Prophylaxis given daily for 6 weeks to an exclusively breastfed infant born to an HIV-positive mother with a suppressed viral load
  5. 6. Maternal treatment given before 18 weeks of gestation to reduce the transmission of Toxoplasma to the fetus
  6. 8. Prophylactic anti-tubercular drug given for 6 months (10 mg/kg/day) to an asymptomatic neonate born to a mother with Tuberculosis
  7. 10. Specific immunoglobulin administered intramuscularly within 12 hours of birth, alongside a vaccine, to infants born to Hepatitis B positive mothers