Perio Part 13

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Across
  1. 2. Derivatives of tetracycline group drugs that lack antimicrobial action but have potent host modulating affects such as inhibiting elevated MMP's pro-inflammatory cytokines and other destructive chemical mediators.
  2. 5. Aim to subject subgingival bacteria to therapeutic levels of an antibacterial drug for a sustained period.
  3. 6. Used in medicine and dentistry to describe the lightly pulling together of wound edges from opposite sides so they appear touching.
  4. 7. Aims to form new cementum new functionally aligned PDL fibers and new alveolar bone.
  5. 11. Doses of an antibiotic that are below the normal bacterial killing or inhibiting doses.
  6. 15. Chlorhexidine gluconate chip is commonly sold under what brand name?
  7. 20. Fill in the Blank: Developement of resistant bacteria and gastrointestinal toxicity seen with antibacterial doses of the tetracyclines is ______ produced by chemically modified tetracyclines.
  8. 21. A condition that makes a particular treatment or procedure potentially inadvisable.
  9. 22. Refers to the degree the margins or edges of the surgical wound relate to each other following surgery but prior to healing.
  10. 23. biochemical mediators that can lead to damage of the periodontium.
  11. 25. Describes the union of a pathologically exposed root with connective tissue or epithelium.
  12. 27. Fill in the Blank: A patient with _________ expectation of periodontal surgery is considered a relative contraindication.
  13. 31. The healing of a periodontal wound by the reunion of the connective tissue and roots where these two tissues have been separated by surgical incision or physical injury but not by disease.
  14. 34. Fill in the Blank: The periodontium cannot be regenerated ___________ in all sites with current periodontal regenerative approaches.
  15. 36. NSAIDs reduce tissue inflammation by inhibiting the action of what?
  16. 37. An mouthrinse ingredient that is a good alternative for patients who cannot tolerate the side effects and allergies associated with chlorhexidine.
  17. 44. Tufted dental floss is great for fixed bridges distal surfaces of the last tooth in the arch proximal surfaces of widely spaced teeth and what type of embrasure spaces?
  18. 45. Fill in the Blank: Regeneration is healing that results in the reestablishment of the ___________ tissues that were present before the disease or damage occurred.
  19. 47. A situation that makes a particular treatment undoubtedly inadvisable.
  20. 50. Healing where the wound is first cleaned by the surgeon and left open deliberately to ensure no infection is apparent before it is closed at a later date.
  21. 51. Doxycycline Hyclate gel is commonly sold under what brand name?
  22. 52. Biologically active compounds stimulated by bacteria that activate the inflammatory response.
  23. 54. A condition that may make periodontal surgery inadvisable.
  24. 57. The most effective antimicrobial agent in mouthrinses for longterm reduction of biofilm and gingivitis.
  25. 58. Medications or agents such as estrogen selective estrogen receptor modulators ad bisphosphonates that reduce bone resorption and helpt to preserve bone mineral density.
  26. 59. The anti-inflammatory biochemical mediators include Interleukin-10 Interleukin-1ra TIMPs and what other cytokine?
  27. 60. Tissue that must form to close the space between the wound margins of tissues that are not closely adapted in order for epithelial cells to grow over the wound.
  28. 61. Meducations used to control elevated cholesterol levels and can also offer some protection against systemic inflammation.
  29. 62. What is the effect of Arestin on bacteria?
  30. 63. Provides enhanced access and visualization to the root surfaces for more thorough periodontal instrumentation.
  31. 64. The mechanism of action of this group of chemical agents used in mouthrinses is the disruption of the cell wall and inhibition of certain bacterial enzymes.
  32. 65. Fill in the Blank: When a patient taking daily doses of NSAIDs for an extended amount of time stops there can be _____________ of the bone loss seen prior to taking the drugs.
Down
  1. 1. This is an expectation for periodontal surgery but is not possible with nonsurgical periodontal therapy.
  2. 3. Healing that takes place when the margins or edges of the wound are not closely adapted or in close contact with eachother.
  3. 4. Refers to a patient not performing adequate biofilm control and can be a relative contraindication for periodontal surgery.
  4. 8. The destruction and death of bone tissue.
  5. 9. Modifying a patient's defense responses to help the body's defenses limit damage caused by disease.
  6. 10. Drugs that inhibit the resorption of bone by altering osteoclastic activity though the mechanism of action for these drugs is not fully understood.
  7. 12. An Matrix Metalloproteinase that can break down collagen.
  8. 13. A surgical procedure in which incisions are made in the gingiva or mucosa to allow for separation of the surface tissues from the underlying tooth roots and alveolar bone.
  9. 14. Periodontal surgery to modify the alveolar bone level or contour.
  10. 16. Functions as a protective mechanism that keeps bacterial infection from doing serious harm to the periodontium.
  11. 17. The pro-inflammatory biochemical mediators include Interleukin-1 ProstaglandinE2 Tumor Necrosis Factor Alpha Matrix Metalloproteinases and what other biochemical mediator?
  12. 18. Fill in the Blank: NSAIDs can reduce inflammation and inhibit _________ activity.
  13. 19. Initials for tissue inhibitors of matrix metalloproteinases
  14. 24. The process of adding specific biomolecules to the diet to improve patient health and the host response to periodontitis.
  15. 26. Biochemical mediators that are protective and limit the bacterial-induced inflammatory response from doing serious harm to the periodontium.
  16. 28. The formation of what structure can be seen in response to surgical or nonsurgical periodontal therapy.
  17. 29. Initials for the major potential side effect associated with bisphosphonate use.
  18. 30. A progressive bone disease that is characterized by a decrease in both bone mass and bone density that can lead to an increased risk of bone fractures.
  19. 32. The generic name for Arestin.
  20. 33. A deformity in the tooth-supporting alveolar bone usually resulting from periodontitis.
  21. 35. Minocycline hydrochloride microspheres are commonly sold under what brand name?
  22. 38. A tetracycline-class antibiotic drug that has been used to treat a varierty of infections and also has other benefits besides its antibiotic effect when used in lower doses.
  23. 39. An important characteristic of mouthrinses and dentrifices where the active ingredient continues to kill periodontal pathogens over an extended number of hours following rinsing.
  24. 40. Refers to the ending of inflammation and healing of the periodontal pocket and can be seen in both periodontal surgery and nonsurgical periodontal therapy.
  25. 41. One of the major building blocks in the periodontium whose breakdown is part of the fundamental pathology of periodontitis.
  26. 42. Occurs when the wound margins or edges are closely adapted to each other.
  27. 43. The initials for drugs that have ben used for many years to treat pain acute inflammation and chronic inflammatory conditions.
  28. 46. Healing of a wound by formation of tissues that do not fully restore the original architecture or original function of the body part.
  29. 48. Medications or agents that stimulate bone formation thereby increasing overall bone mineral density.
  30. 49. Unwaxed or waxed thread made of silk nylon or plastic monofilament fibers.
  31. 53. The reconstitution of new tissue.
  32. 54. Anti-inflammatory mediators derived from Omega-3 fatty acids that work to resolve inflammation to reduce the risk of tissue breakdown and attachment loss.
  33. 55. How many times a day should a periodontitis patient take low dose doxycycline for it to be effective?
  34. 56. Surgical procedures that simply cut away and remove some of the periodontal tissues.