Persistent Infections 2024

123456789101112131415161718192021222324
Across
  1. 2. transport direction of the HSV viral capsids in the sensory neurons during reactivation
  2. 6. circularize silent or quiet herpesvirus genome.
  3. 8. transcribed from HSV episome during latency in ganglia.
  4. 10. Cells where Epstein-Barr Virus establish latency and reactivates.
  5. 12. reactivation of Varicella-Zoster virus causes rash that is restricted to the area of skin that is innervated by the affected ganglia. Severe pain.
  6. 13. state of a herpesvirus infection where viral particles are not produced.
  7. 14. fatal disease cause by a persistent pathogenic HIV infection.
  8. 16. early infection with Varicella-Zoster virus cause wise spread skin rash, fatigue, fever, and itching.
  9. 19. transport direction of the HSV viral capsids in sensory neurons during latency
  10. 20. infection that last for the life of the host.
  11. 21. State of patients that persistent infection with human polyomavirus (JCV and BK) results in deadly disease.
  12. 22. Herpesvirus that crosses the placenta and causes congenital defects and death of the newborn.
  13. 24. rapid and self-limiting infection
Down
  1. 1. Site of Herpes simplex virus latency.
  2. 2. subfamily of neurotropic human herpesvirus
  3. 3. host histone contribution to reactivation of viral genome transcription.
  4. 4. subfamily lymphotropic herpesvirus human herpesvirus
  5. 5. Herpesvirus that causes infectious mononucleosis a benign proliferation of B-lymphocytes.
  6. 7. host histone contribution to maintenance silence viral episome
  7. 9. Human cytomegalovirus (HCMV) establish latency in bone marrow __________.
  8. 11. immune cells that are first latently infected with HIV and 15 to 30 years later are depleted.
  9. 15. virus that interfere with the assembly and transport of the MHC-1 protein and viral peptides to evade CTL response.
  10. 17. host that sustain persistent asymptomatic infections with polyomavirus.
  11. 18. Binds to receptors in activated CTLs to activate apoptosis of the effector immune cells.
  12. 23. subfamily of lymphotropic and oncogenic human herpesvirus