Pharmacodynamics

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Across
  1. 6. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the
  2. 7. Ligands typically recognise and bind to?
  3. 9. An example of a drug that acts on ion channels is
  4. 12. Most drugs display preference for one subtype of receptor over others this is referred to as?
  5. 13. Enzymes typically act as catalysts to facilitate the conversion of what into products
  6. 14. Relates to the mechanism of action of medicines
  7. 15. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug A is acting how?
  8. 17. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug that stimulates the receptor, it is?
  9. 18. Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site and are called?
  10. 19. A drug that can produce a greater therapeutic response in a patient regardless of the amount given
Down
  1. 1. A drug can be described as this if it causes a similar response compared to another drug at a lower dose
  2. 2. The strength of the binding interaction between a drug and its molecular target is defined as
  3. 3. A drug that activates a receptor
  4. 4. The ability to produce an effect on a particular target tissue
  5. 5. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
  6. 8. An example of an allosteric modulator is a class of drugs called?
  7. 10. Drug that attaches to a receptor, does not initiate an action
  8. 11. The shape of the log graph is a what curve
  9. 16. On the dose-response curve the maximum effect is called the