pharmacodynamics115

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Across
  1. 3. A drug that activates a receptor
  2. 4. the amount of drug required to produce 50% of that drug's maximal effect; the more potent the drug, the lower the dose required for a given effect.
  3. 8. An example of an allosteric modulator is a class of drugs called?
  4. 12. An example of a drug that acts on ion channels is?
  5. 13. An abbreviation for Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site are called
  6. 14. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the
  7. 15. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug
  8. 16. Drug that attaches to a receptor, but does not initiate an action
  9. 17. The strength of the binding interaction between a drug and its molecular target is defined as?
Down
  1. 1. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug A is acting how?
  2. 2. Most drugs display preference for one subtype of receptor over others this is referred to as?
  3. 4. Relates to the mechanism of action of medicines
  4. 5. The ability to produce an effect on a particular target tissue
  5. 6. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
  6. 7. the ability of a drug to achieve the desired therapeutic effect
  7. 9. Doug determines the relative safety of a drug in terms of a ratio between its lethal dose and its effective dose. This measure is called the therapeutic _____.
  8. 10. Ligands typically recognise and bind to?
  9. 11. Enzymes typically act as catalysts to facilitate the conversion of what into products