pharmacodynamics115

2. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug
4. An abbreviation for Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site are called
7. relates to the amount of chemical required to produce an effect
8. Ligands typically recognise and bind to?
10. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug B is a (two-words)?
12. Enzymes typically act as catalysts to facilitate the conversion of what into products

1. Relates to the mechanism of action of medicines
3. the ability of a drug to achieve the desired therapeutic effect
4. Drug that attaches to a receptor, but does not initiate an action
5. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
6. refers to the narrowness of a drug's range of actions on particular receptors, cellular processes or tissues
9. Doug determines the relative safety of a drug in terms of a ratio between its lethal dose and its effective dose. This measure is called the therapeutic _____.
11. The strength of the binding interaction between a drug and its molecular target is defined as?
13. A drug that activates a receptor
14. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the